Komlos L, Ben-Efraim S, Lewis N J, Hart J, Halbrecht I
Int J Immunopharmacol. 1984;6(6):593-9. doi: 10.1016/0192-0561(84)90070-5.
The effect of N-acetyl-D-glucosamine (NAG) on in vitro stimulated human peripheral blood lymphocytes was investigated. NAG was added to lymphocyte cultures stimulated by the mitogen PHA, the antigen PPD or to one-way-stimulated mixed lymphocyte cultures from unrelated donors. The results indicate that NAG (1-2 micrograms/ml) in appropriate experimental conditions has an enhancing effect on DNA and protein synthesis induced by PHA, PPD and allogeneic cells. Addition of NAG (1-2 micrograms/ml) to unstimulated lymphocyte cultures had no effect on DNA or protein synthesis.
研究了N-乙酰-D-葡萄糖胺（NAG）对体外刺激的人外周血淋巴细胞的影响。将NAG添加到由丝裂原PHA、抗原PPD刺激的淋巴细胞培养物中，或添加到来自无关供体的单向刺激混合淋巴细胞培养物中。结果表明，在适当的实验条件下，NAG（1-2微克/毫升）对PHA、PPD和同种异体细胞诱导的DNA和蛋白质合成具有增强作用。向未刺激的淋巴细胞培养物中添加NAG（1-2微克/毫升）对DNA或蛋白质合成没有影响。
