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细菌磷酸转移酶系统酶成分编码基因的调控

Regulation of genes coding for enzyme constituents of the bacterial phosphotransferase system.

作者信息

Rephaeli A W, Saier M H

出版信息

J Bacteriol. 1980 Feb;141(2):658-63. doi: 10.1128/jb.141.2.658-663.1980.

Abstract

Regulation of the synthesis of the proteins of the phosphoenolpyruvate:sugar phosphotransferase system was systematically studied in wild-type and mutant strains of Salmonella typhimurium and Escherichia coli. The results suggest that enzyme I and HPr as well as the glucose-specific and the mannose-specific enzymes II are synthesized by a mechanism which depends on (i) cyclic adenosine monophosphate and its receptor protein; (ii) extracellular inducer; (iii) the sugar-specific enzyme II complex which recognizes the inducing sugar; and (iv) the general energy-coupling proteins of the phosphotransferase system, enzyme I and HPr.

摘要

在鼠伤寒沙门氏菌和大肠杆菌的野生型及突变株中,对磷酸烯醇丙酮酸:糖磷酸转移酶系统蛋白质合成的调控进行了系统研究。结果表明,酶I、HPr以及葡萄糖特异性和甘露糖特异性的酶II是通过一种依赖于以下因素的机制合成的:(i)环磷酸腺苷及其受体蛋白;(ii)细胞外诱导剂;(iii)识别诱导糖的糖特异性酶II复合物;以及(iv)磷酸转移酶系统的一般能量偶联蛋白,即酶I和HPr。

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Regulation of genes coding for enzyme constituents of the bacterial phosphotransferase system.
J Bacteriol. 1980 Feb;141(2):658-63. doi: 10.1128/jb.141.2.658-663.1980.

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