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禽肉瘤前病毒DNA序列在非允许性XC细胞中发生修饰，而在允许性鸡细胞中则不然。

Modification of avian sarcoma proviral DNA sequences in nonpermissive XC cells but not in permissive chicken cells.

作者信息

Guntaka R V, Rao P Y, Mitsialis S A, Katz R

出版信息

J Virol. 1980 May;34(2):569-72. doi: 10.1128/JVI.34.2.569-572.1980.

DOI:10.1128/JVI.34.2.569-572.1980
PMID:6246282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC288737/
Abstract

For the first time, we present evidence with restriction enzymes HpaII and MspI which indicates that the proviral DNA sequence of avian sarcoma virus is modified by methylation in a nonpermissive rat cell line but not in permissive chicken cells. Some of the endogenous viral sequences in the permissive cells were also methylated. No 5-methylcytosine could be detected in the unintegrated viral DNA.

摘要

我们首次用限制性内切酶HpaII和MspI提供了证据，表明禽肉瘤病毒的前病毒DNA序列在非允许性大鼠细胞系中会因甲基化而发生修饰，但在允许性鸡细胞中则不会。允许性细胞中的一些内源性病毒序列也发生了甲基化。在未整合的病毒DNA中未检测到5-甲基胞嘧啶。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e09f/288737/7af795f6b280/jvirol00173-0277-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e09f/288737/e8881d67dedb/jvirol00173-0276-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e09f/288737/7af795f6b280/jvirol00173-0277-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e09f/288737/e8881d67dedb/jvirol00173-0276-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e09f/288737/7af795f6b280/jvirol00173-0277-a.jpg

相似文献

1
Modification of avian sarcoma proviral DNA sequences in nonpermissive XC cells but not in permissive chicken cells.禽肉瘤前病毒DNA序列在非允许性XC细胞中发生修饰，而在允许性鸡细胞中则不然。
J Virol. 1980 May;34(2):569-72. doi: 10.1128/JVI.34.2.569-572.1980.
2
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J Gen Virol. 1987 May;68 ( Pt 5):1485-90. doi: 10.1099/0022-1317-68-5-1485.
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本文引用的文献

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Presence of chicken tumour virus in the sarcoma of the adult rat inoculated after birth with Rous sarcoma tissue.出生后接种劳斯肉瘤组织的成年大鼠肉瘤中鸡肿瘤病毒的存在情况。
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Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts.劳斯肉瘤病毒特异性脱氧核糖核酸在允许性宿主和非允许性宿主感染后的整合。
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Expression of a cloned adenovirus gene is inhibited by in vitro methylation.克隆腺病毒基因的表达受到体外甲基化的抑制。
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DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.DNA甲基化与基因表达：分子克隆后内源性逆转录病毒基因组具有感染性。
Proc Natl Acad Sci U S A. 1981 Dec;78(12):7609-13. doi: 10.1073/pnas.78.12.7609.
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Evidence for methylation of inactive human rRNA genes in amplified regions.扩增区域中失活的人类核糖体RNA基因甲基化的证据。
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Methylation patterns of repetitive DNA sequences in germ cells of Mus musculus.小家鼠生殖细胞中重复DNA序列的甲基化模式。
Nucleic Acids Res. 1984 Mar 26;12(6):2823-36. doi: 10.1093/nar/12.6.2823.
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An upstream regulatory domain of avian tumor virus long terminal repeat is required for the expression of a procaryotic neomycin gene in eucaryotic cells.禽肿瘤病毒长末端重复序列的上游调控结构域是真核细胞中表达原核新霉素基因所必需的。
Mol Cell Biol. 1983 Nov;3(11):1975-84. doi: 10.1128/mcb.3.11.1975-1984.1983.
9
Orientation and position of avian leukosis virus DNA relative to the cellular oncogene c-myc in B-lymphoma tumors of highly susceptible 15I5 X 7(2) chickens.高易感性15I5 X 7(2)鸡B淋巴瘤肿瘤中禽白血病病毒DNA相对于细胞癌基因c-myc的定位与位置
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10
Hypomethylation of Epstein-Barr virus DNA in the nonproducer B-cell line EBR.非产生性B细胞系EBR中爱泼斯坦-巴尔病毒DNA的低甲基化
J Virol. 1982 Sep;43(3):1129-31. doi: 10.1128/JVI.43.3.1129-1131.1982.
用来自产病毒哺乳动物细胞的DNA单次转染鸡成纤维细胞。
J Gen Virol. 1973 Oct;21:47-55. doi: 10.1099/0022-1317-21-1-47.
4
RNA and DNA forms of the genetic material of C-type viruses and the integrated state of the DNA form in the cellular chromosome.C型病毒遗传物质的RNA和DNA形式以及DNA形式在细胞染色体中的整合状态。
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Detection of specific sequences among DNA fragments separated by gel electrophoresis.在通过凝胶电泳分离的DNA片段中检测特定序列。
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6
A physical map of the DNA regions flanking the rabbit beta-globin gene.兔β-珠蛋白基因侧翼DNA区域的物理图谱。
Cell. 1977 Oct;12(2):429-39. doi: 10.1016/0092-8674(77)90119-2.
7
MspI, an isoschizomer of hpaII which cleaves both unmethylated and methylated hpaII sites.MspI，hpaII的同裂酶，可切割未甲基化和甲基化的hpaII位点。
Nucleic Acids Res. 1978 Sep;5(9):3231-6. doi: 10.1093/nar/5.9.3231.
8
Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12-transformed hamster cells.12型腺病毒转化的仓鼠细胞基因组中病毒DNA序列的整合模式
Cell. 1978 Jul;14(3):569-85. doi: 10.1016/0092-8674(78)90243-x.
9
Use of restriction enzymes to study eukaryotic DNA methylation: I. The methylation pattern in ribosomal DNA from Xenopus laevis.利用限制性内切酶研究真核生物DNA甲基化：I. 非洲爪蟾核糖体DNA中的甲基化模式
J Mol Biol. 1978 Jan 5;118(1):27-47. doi: 10.1016/0022-2836(78)90242-5.
10
Specificity of Hpa II and Hae III DNA methylases.Hpa II和Hae III DNA甲基化酶的特异性。
Nucleic Acids Res. 1977 Dec;4(12):4211-21. doi: 10.1093/nar/4.12.4211.