Bull World Health Organ. 1980;58(2):183-98.
Recent evidence indicates that viruses are an important cause of acute diarrhoea in infants and young children in both developed and developing countries. This article reviews the available information on the epidemiology, clinical features, and laboratory diagnosis of acute diarrhoea due to two of the more important and recently discovered viruses, namely rotaviruses and the Norwalk and Norwalk-like agents, or to other viral agents. Research priorities are also recommended that will help to elucidate the epidemiology, pathophysiology, and means of preventing viral diarrhoeas. Foremost among these research priorities is the development of a rotavirus vaccine for use in man.
最近的证据表明,在发达国家和发展中国家,病毒都是婴幼儿急性腹泻的一个重要病因。本文综述了有关两种较为重要且最近才发现的病毒,即轮状病毒和诺沃克病毒及诺沃克样因子,或其他病毒病原体所致急性腹泻的流行病学、临床特征和实验室诊断方面的现有信息。还推荐了一些研究重点,这将有助于阐明病毒腹泻的流行病学、病理生理学及预防方法。这些研究重点中最为重要的是开发一种供人类使用的轮状病毒疫苗。