Stalder H
Schweiz Med Wochenschr. 1982 Apr 12;112(15):511-5.
Viruses are one of the most frequent causes of acute infectious gastroenteritis. Thus, rotaviruses are responsible for 40-60%--and in winter sometimes for over 90% - of diarrhoea in infants. These viruses may also cause disease in adults, but small viruses of a size of about 27 nm, such as the Norwalk agent, play a much more important role. Several other non-cultivable viruses such as adeno-, calici- and astroviruses have been implicated as a cause of infectious diarrhoea. Knowledge of rotaviruses is so far advanced that routine laboratory diagnosis can easily be performed and active immunization against rotavirus infection envisaged.
病毒是急性感染性肠胃炎最常见的病因之一。因此,轮状病毒导致40%-60%的婴儿腹泻——在冬季有时超过90%。这些病毒也可能在成人中引发疾病,但大小约为27纳米的小型病毒,如诺沃克病毒,发挥着更为重要的作用。其他几种不可培养的病毒,如腺病毒、杯状病毒和星状病毒,也被认为是感染性腹泻的病因。目前对轮状病毒的了解已经相当深入,常规实验室诊断很容易进行,针对轮状病毒感染的主动免疫也在设想之中。