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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Menge H, Murer H, Robinson J W

J Physiol. 1978 Jan;274:9-16. doi: 10.1113/jphysiol.1978.sp012130.

The functional properties of the ileal mucosa following jejunal resection or interposition in the jejunum were studied with the help of membrane vesicles. 2. Despite the development of functional and morphological features in the mucosa which are more generally associated with the jejunum than with the ileum, examination of brush-border vesicles derived from ileal and jejunal enterocytes from resected or transposed intestines reveals that the functional characteristics of apical membranes isolated from the different regions of the intestine are maintained after these surgical manoeuvres. Vesicles from control ileum develop an 'overshoot' uptake of glucose that is 3-4 times smaller than that of jejunal vesicles, a difference that is still observed in membranes prepared from mucosa of ileal loops following proximal resection or interposition in the jejunum.

借助膜泡研究了空肠切除或空肠间置术后回肠黏膜的功能特性。2. 尽管黏膜中出现了通常与空肠而非回肠相关的功能和形态特征，但对切除或移位肠道的回肠和空肠肠上皮细胞来源的刷状缘膜泡进行检测发现，在这些手术操作后，从肠道不同区域分离的顶端膜的功能特性得以保留。对照回肠的膜泡对葡萄糖的“过冲”摄取量比空肠膜泡小3 - 4倍，在近端切除或空肠间置术后回肠袢黏膜制备的膜中仍可观察到这种差异。

Menge H, Murer H, Robinson J W

J Physiol. 1978 Jan;274:9-16. doi: 10.1113/jphysiol.1978.sp012130.

The functional properties of the ileal mucosa following jejunal resection or interposition in the jejunum were studied with the help of membrane vesicles. 2. Despite the development of functional and morphological features in the mucosa which are more generally associated with the jejunum than with the ileum, examination of brush-border vesicles derived from ileal and jejunal enterocytes from resected or transposed intestines reveals that the functional characteristics of apical membranes isolated from the different regions of the intestine are maintained after these surgical manoeuvres. Vesicles from control ileum develop an 'overshoot' uptake of glucose that is 3-4 times smaller than that of jejunal vesicles, a difference that is still observed in membranes prepared from mucosa of ileal loops following proximal resection or interposition in the jejunum.

借助膜泡研究了空肠切除或空肠间置术后回肠黏膜的功能特性。2. 尽管黏膜中出现了通常与空肠而非回肠相关的功能和形态特征，但对切除或移位肠道的回肠和空肠肠上皮细胞来源的刷状缘膜泡进行检测发现，在这些手术操作后，从肠道不同区域分离的顶端膜的功能特性得以保留。对照回肠的膜泡对葡萄糖的“过冲”摄取量比空肠膜泡小3 - 4倍，在近端切除或空肠间置术后回肠袢黏膜制备的膜中仍可观察到这种差异。