Caspary L, Schindling B, Dundarov S, Falke D
Arch Virol. 1980;65(3-4):219-27. doi: 10.1007/BF01314538.
The spread of HSV of type 1 and 2 was investigated after intraperitoneal, intraplantar and intracerebral infections of resistant (C57/bl) and susceptible (NMRI) mice. The virus spreads after i.p. infection to the spleen and the liver to the same extent in both strains of mice. However, virus is eliminated earlier in resistant mice. Intracerebral infections revealed a peculiar type of resistance of C57/bl mice especially for type 2 of HSV. HSV multiplies in the thymus at the early stage of infection and can be detected in this organ in sick mice of NMRI strain. HSV-1 and 2 can be detected in the spinal cord of C57/bl mice without sickness or death of these animals.
在对抗性（C57/bl）和易感（NMRI）小鼠进行腹腔内、足底和脑内感染后，研究了1型和2型单纯疱疹病毒（HSV）的传播情况。在腹腔内感染后，病毒在两种品系小鼠中传播至脾脏和肝脏的程度相同。然而，抗性小鼠体内的病毒清除得更早。脑内感染显示C57/bl小鼠具有一种特殊类型的抗性，尤其是对2型HSV。HSV在感染早期在胸腺中增殖，并且可以在NMRI品系的患病小鼠的该器官中检测到。在C57/bl小鼠的脊髓中可以检测到HSV-1和2，而这些动物没有患病或死亡。
