小家鼠莫洛辛努斯内源性亲嗜性病毒与AKR病毒之间的高度相似性。
Close similarity between endogenous ecotropic virus of Mus musculus molossinus and AKR virus.
作者信息
Chattopadhyay S K, Lander M R, Rowe W P
出版信息
J Virol. 1980 Nov;36(2):499-505. doi: 10.1128/JVI.36.2.499-505.1980.
Abstract
By using seven different restriction endonucleases, the cleavage patterns of the unintegrated provioral DNA from an ecotropic murine leukemia virus isolated from Mus musculus molossinus were found to be identical to those of AKR virus. An AKR [3H]DNA probe can be completely saturated with M. musculus molossinus and M. musculus castaneus DNAs, although the arrangement of viral sequences in M. musculus molossinus DNA differed from that of AKR virus. These studies indicate that an AKR-type ecotropic virus is present in some wild Asiatic mice.
摘要
通过使用七种不同的限制性内切核酸酶，发现从小家鼠的小家鼠亚种分离出的亲嗜性鼠白血病病毒的未整合前病毒DNA的切割模式与AKR病毒的切割模式相同。尽管小家鼠DNA中病毒序列的排列与AKR病毒不同，但AKR [3H]DNA探针可以被小家鼠和栗色小家鼠的DNA完全饱和。这些研究表明，某些野生亚洲小鼠中存在AKR型亲嗜性病毒。
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