Kay R M
Can Med Assoc J. 1980 Dec 20;123(12):1213-7.
Epidemiologic studies have suggested that dietary fibre protects humans against coronary heart disease, but interpretation of the data is confounded by coexisting differences in both dietary and environmental variables. The hypocholesterolemic action of dietary fibre varies: in general mucilaginous fibres such as pectin and oat bran are more effective than particulate fibres such as wheat bran. Although the mechanism of action of mucilaginous fibres is not completely understood, there is evidence that they induce small increases in the fecal excretion of bile acids and neutral steroids that are not fully compensated for by de novo cholesterol synthesis.
流行病学研究表明,膳食纤维可保护人类预防冠心病,但这些数据的解读因饮食和环境变量中同时存在的差异而变得复杂。膳食纤维的降胆固醇作用各不相同:一般来说,果胶和燕麦麸等粘性纤维比麦麸等颗粒纤维更有效。虽然粘性纤维的作用机制尚未完全了解,但有证据表明,它们会使胆汁酸和中性类固醇的粪便排泄量略有增加,而新合成胆固醇并不能完全补偿这一增加量。