Chandra H, Gupta B N, Bhargava S K, Clerk S H, Mahendra P N
J Anal Toxicol. 1980 Jul-Aug;4(4):161-5. doi: 10.1093/jat/4.4.161.
A study was undertaken to assess the health status of workers exposed to cyanide fumes and cyanide aerosols in one of the local factories. Cyanide levels in the breathing zone and the working atmosphere were measured. Cyanide and thiocyanate concentrations in blood and urine were determined colorimetrically. The cyanide and thiocyanate concentrations in blood and urine of exposed workers were much higher than those of control workers. Smokers had higher concentrations than nonsmokers. The highest values of cyanide were found to be 0.8 and 0.2 mg/m3 in the breathing zone and general workroom atmosphere respectively. In spite of such low values, the workers complained of typical HCN poisoning. It is suggested that MAC values of 5 mg/m3 (in terms of CN) should be reviewed in respect to conditions in India.
一项研究旨在评估当地一家工厂中接触氰化物烟雾和气溶胶的工人的健康状况。测量了呼吸区域和工作环境中的氰化物水平。采用比色法测定血液和尿液中的氰化物和硫氰酸盐浓度。接触组工人血液和尿液中的氰化物和硫氰酸盐浓度远高于对照组工人。吸烟者的浓度高于不吸烟者。呼吸区域和一般车间空气中氰化物的最高值分别为0.8和0.2毫克/立方米。尽管数值如此之低,但工人们仍抱怨有典型的氰化氢中毒症状。建议根据印度的情况对5毫克/立方米(以氰化物计)的最高容许浓度值进行审查。