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黑腹果蝇的移动分散遗传元件MDG1:结构组织

Mobile dispersed genetic element MDG1 of Drosophila melanogaster: structural organization.

作者信息

Ilyin Y V, Chmeliauskaite V G, Ananiev E V, Lyubomirskaya N V, Kulguskin V V, Bayev A A, Georgiev G P

出版信息

Nucleic Acids Res. 1980 Nov 25;8(22):5333-46. doi: 10.1093/nar/8.22.5333.

Abstract

The whole-length mobile dispersed genetic element mdg1 has been cloned from D. melanogaster genome. It contains DNA fragments described earlier as Dm225 and Dm234, Mdg1 is 7.2 kb long and framed with two direct repeats of 300-400 base pairs each. Mdg1 family is represented by about 25 copies in the genome of flies and by 200 copies in the genome of cultured cell line 67J25D. Virtually all the copies in the genome of D. melanogaster have the same restriction map. Oligo(dA)-oligo(dT) regions were found within mdg1.

摘要

全长可移动分散遗传元件mdg1已从黑腹果蝇基因组中克隆出来。它包含先前描述为Dm225和Dm234的DNA片段,mdg1长7.2 kb,两侧各有两个300 - 400个碱基对的正向重复序列。mdg1家族在果蝇基因组中约有25个拷贝,在培养细胞系67J25D的基因组中有200个拷贝。实际上,黑腹果蝇基因组中的所有拷贝都具有相同的限制性图谱。在mdg1内发现了寡聚(dA)-寡聚(dT)区域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce36/324305/97a5bb4b30c6/nar00439-0203-a.jpg

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