Pierce R J, Brown D J, Denison D M
Thorax. 1980 Oct;35(10):773-80. doi: 10.1136/thx.35.10.773.
We describe a method of separately determining the volumes of the right and left lungs from conventional chest radiographs and of determining the volumes of individual lobes and pathological spaces, whenever their boundaries are visible radiologically or can be displayed scintigraphically--for example, during fibreoptic bronchoscopy. Scintigrams of individual lungs, lobes, and segments are obtained by deflecting a stream of air marked with 81m krypton down the suction channel of the bronchoscope into the appropriate bronchus during inspiration, followed by a breath-hold during which the image is recorded with a gamma camera. Both radiographic and scintigraphic methods have been validated by comparison with argon dilution estimates of individual lung and lobar volumes also obtained at bronchoscopy, and results for the three methods in normal subjects are presented. Used in conjunction with bronchoscopic soluble gas uptake studies, these volume measurements permit precise estimation of effective perfusion, tissue and water volume, and gas transfer at lobar and segmental level. Individual lung and lobar volumes can be used to quantify lung and lobar collapse and compression, mediastinal shift, regional ventilation and gas trapping, and phrenic paresis.
我们描述了一种从传统胸部X光片中分别测定右肺和左肺体积的方法，以及在影像学上可见或可通过闪烁扫描显示其边界时（例如在纤维支气管镜检查期间）测定各个肺叶和病理腔隙体积的方法。在吸气时，将标记有氪-81m的气流沿支气管镜的吸引通道向下导入适当的支气管，随后屏气，在此期间用γ相机记录图像，从而获得各个肺、肺叶和肺段的闪烁扫描图。通过与在支气管镜检查时也获得的个体肺和肺叶体积的氩稀释估计值进行比较，验证了放射学和闪烁扫描方法，并且给出了正常受试者三种方法的结果。这些体积测量与支气管镜可溶性气体摄取研究结合使用时，可精确估计叶和段水平的有效灌注、组织和水体积以及气体转移。个体肺和肺叶体积可用于量化肺和肺叶的萎陷与压缩、纵隔移位、区域通气和气体潴留以及膈神经麻痹。
