Stensland E, Sandberg S, Berge R, Aarli J A, Romslo I
Acta Neurol Scand. 1981 Jan;63(1):51-6. doi: 10.1111/j.1600-0404.1981.tb00748.x.
The activities of adenylate kinase, creatine kinase and lactate dehydrogenase were measured in cerebrospinal fluid and serum from 127 patients admitted to the Department of Neurology. All cerebrospinal fluid samples with hemoglobin greater than 1 mg/l were excluded. Upper reference limits for the enzyme determinations were established, using samples from patients without objective criteria of organic involvement of the nervous system. High enzyme activities did not correlate to any particular group of diseases and were also found in patients without organic brain diseases. We conclude that determination of the three enzymes in cerebrospinal fluid is of limited value in the diagnosis of neurological diseases.
对神经内科收治的127例患者的脑脊液和血清中的腺苷酸激酶、肌酸激酶及乳酸脱氢酶活性进行了测定。所有血红蛋白含量大于1mg/l的脑脊液样本均被排除。利用无神经系统器质性病变客观标准的患者样本，确定了酶测定的参考上限。高酶活性与任何特定疾病组均无相关性，在无器质性脑病的患者中也有发现。我们得出结论，脑脊液中这三种酶的测定在神经系统疾病诊断中的价值有限。
