• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

头部损伤中脑脊液的病理生理学:第2部分。中枢神经系统创伤的生化标志物。

Pathophysiology of cerebrospinal fluid in head injury: Part 2. Biochemical markers for central nervous system trauma.

作者信息

Bakay R A, Sweeney K M, Wood J H

出版信息

Neurosurgery. 1986 Mar;18(3):376-82. doi: 10.1227/00006123-198603000-00026.

DOI:10.1227/00006123-198603000-00026
PMID:3010171
Abstract

Many substances are released into the cerebrospinal fluid after head injury. The study of these substances and their relationship to the severity and outcome of head trauma has lead to the search for biochemical markers to aid in the quantification of the severity of the lesion and serve as a prognostic guide. The authors review the potential usefulness of biochemical markers, qualities of an ideal marker, and several potential enzymes that may be utilized as markers in central nervous system trauma.

摘要

头部受伤后,许多物质会释放到脑脊液中。对这些物质及其与头部创伤严重程度和预后关系的研究,促使人们寻找生化标志物,以帮助量化损伤的严重程度并作为预后指导。作者回顾了生化标志物的潜在用途、理想标志物的特性,以及几种可能用作中枢神经系统创伤标志物的潜在酶。

相似文献

1
Pathophysiology of cerebrospinal fluid in head injury: Part 2. Biochemical markers for central nervous system trauma.头部损伤中脑脊液的病理生理学:第2部分。中枢神经系统创伤的生化标志物。
Neurosurgery. 1986 Mar;18(3):376-82. doi: 10.1227/00006123-198603000-00026.
2
[Biochemical markers of the brain injury].[脑损伤的生化标志物]
Agressologie. 1988 Apr;29(4):233-5.
3
Biochemical markers of central nervous system tumors in cerebrospinal fluid.
Ann Clin Lab Sci. 1978 Nov-Dec;8(6):459-66.
4
Levels of enolase and other enzymes in the cerebrospinal fluid as indices of pathological change.脑脊液中烯醇化酶及其他酶的水平作为病理变化指标。
J Neurol Neurosurg Psychiatry. 1981 Dec;44(12):1129-35. doi: 10.1136/jnnp.44.12.1129.
5
MR and cerebrospinal fluid enzymes as sensitive indicators of subclinical cerebral injury after open-heart valve replacement surgery.磁共振成像和脑脊液酶作为心脏瓣膜置换术后亚临床脑损伤的敏感指标。
AJNR Am J Neuroradiol. 1996 Feb;17(2):205-12; discussion 213-5.
6
Creatine kinase and lactate dehydrogenase in the cerebrospinal fluid in patients with head injuries.
Acta Neurochir (Wien). 1975;32(3-4):209-17. doi: 10.1007/BF01405454.
7
Cerebrospinal fluid enzymes in neurological diseases.神经疾病中的脑脊液酶
Acta Neurol Scand. 1981 Jan;63(1):51-6. doi: 10.1111/j.1600-0404.1981.tb00748.x.
8
Cerebrospinal fluid enzymes in acute brain injury. 2. Relation of CSF enzyme activity to extent of brain injury.急性脑损伤中的脑脊液酶。2. 脑脊液酶活性与脑损伤程度的关系。
J Neurol Neurosurg Psychiatry. 1977 Jul;40(7):666-74. doi: 10.1136/jnnp.40.7.666.
9
Systematic review of prediction of poor outcome in anoxic-ischaemic coma with biochemical markers of brain damage.脑损伤生化标志物预测缺氧缺血性昏迷不良预后的系统评价
Intensive Care Med. 2001 Oct;27(10):1661-7. doi: 10.1007/s001340101076.
10
Changes in cerebrospinal fluid enzyme activity after severe head injury. Diagnostic and prognostic values.重型颅脑损伤后脑脊液酶活性的变化。诊断及预后价值。
Acta Anaesthesiol Belg. 1984 Mar;35(1):79-86.

引用本文的文献

1
Metabolomics Profiling As a Diagnostic Tool in Severe Traumatic Brain Injury.代谢组学分析作为重症创伤性脑损伤的诊断工具
Front Neurol. 2017 Aug 18;8:398. doi: 10.3389/fneur.2017.00398. eCollection 2017.
2
Biochemical changes in the injured brain.受损大脑中的生化变化。
World J Biol Chem. 2017 Feb 26;8(1):21-31. doi: 10.4331/wjbc.v8.i1.21.
3
Neuronal and glial markers are differently associated with computed tomography findings and outcome in patients with severe traumatic brain injury: a case control study.神经元和神经胶质标志物与严重创伤性脑损伤患者的计算机断层扫描结果和预后的相关性不同:一项病例对照研究。
Crit Care. 2011 Jun 24;15(3):R156. doi: 10.1186/cc10286.
4
Reliability of S100B in predicting severity of central nervous system injury.S100B在预测中枢神经系统损伤严重程度方面的可靠性。
Neurocrit Care. 2007;6(2):121-38. doi: 10.1007/s12028-007-0008-x.
5
The significance of neuron specific enolase levels in cerebrospinal fluid and serum after experimental traumatic brain damage.
Acta Neurochir (Wien). 1995;135(3-4):141-3. doi: 10.1007/BF02187758.
6
Creatine-kinase-BB after severe head-injury as an index of prognosis in relation to nature of trauma and patients age.
Acta Neurochir (Wien). 1989;101(3-4):117-20. doi: 10.1007/BF01410525.
7
Increases of neuron-specific enolase, S-100 protein, creatine kinase and creatine kinase BB isoenzyme in CSF following intraventricular catheter implantation.脑室内导管植入后脑脊液中神经元特异性烯醇化酶、S-100蛋白、肌酸激酶及肌酸激酶BB同工酶水平升高。
Acta Neurochir (Wien). 1991;110(3-4):106-9. doi: 10.1007/BF01400675.
8
Increased serum creatine kinase BB and neuron specific enolase following head injury indicates brain damage.
Acta Neurochir (Wien). 1992;115(3-4):106-11. doi: 10.1007/BF01406367.