Meister P, Nathrath W
Diagn Histopathol. 1981 Jan-Mar;4(1):79-87.
Immunohistochemical labelling of histiocytic tumour cells in formalin-fixed paraffin-embedded material was usefully applied to malignant fibrous histiocytoma (MFH) and to malignant histiocytosis (MH). Not all cases of MFH showed a positive reaction, in contrast with the obligatory positive staining in MH. In general, histiocytic tumour cells stained more intensively with alpha 1-antichymotrypsin than with lysozyme. False positive results can be due to intermingled non-neoplastic histiocytes or degenerating neoplastic cells in any mesenchymal tumour.
免疫组织化学标记在福尔马林固定石蜡包埋材料中的组织细胞肿瘤细胞，已有效地应用于恶性纤维组织细胞瘤（MFH）和恶性组织细胞增多症（MH）。与MH中必然出现的阳性染色不同，并非所有MFH病例都显示阳性反应。一般来说，组织细胞肿瘤细胞用α1-抗糜蛋白酶染色比用溶菌酶染色更强烈。假阳性结果可能是由于任何间充质肿瘤中混杂的非肿瘤性组织细胞或变性的肿瘤细胞所致。
