心内膜心肌活检诊断价值的批判性评估。心脏活检评估。

MacKay E H, Littler W A, Sleight P

Br Heart J. 1978 Jan;40(1):69-78. doi: 10.1136/hrt.40.1.69.

Right or left ventricular endomyocardial biopsy with the Konno or the Olympus bioptome was attempted in 73 patients aged 5 months to 61 years, with 82 per cent success. Light and electron microscopy showed non-specific features in over half the biopsies with new or diagnostically useful information in only 10 per cent of cases, usually as a result of electron microscopy. The method is safe but is of strictly limited diagnostic value and is likely to be of most help as a research tool in the biochemical study of cardiomyopathies.

我们使用Konno活检钳或奥林巴斯活检钳对73例年龄在5个月至61岁的患者进行了右心室或左心室心内膜活检，成功率为82%。光镜和电镜检查显示，超过半数的活检标本呈现非特异性特征，只有10%的病例获得了新的或具有诊断价值的信息，这些信息通常来自电镜检查。该方法安全，但诊断价值极为有限，作为心肌病生化研究的一种研究工具可能最有帮助。