Tachibana H, Wada A, Gotoh O, Takanami M
Biochim Biophys Acta. 1978 Feb 16;517(2):319-28. doi: 10.1016/0005-2787(78)90198-3.
Differential melting profiles of the linear replicative form (RF-III) DNA of bacteriophage fd, of the fragments obtained by the restriction endonuclease R.HinHI and of those obtained by R.Hga were investigated. With these results a physical map which locates the cooperative melting regions on the DNA was constructed, and compared with the genetic map.
研究了噬菌体fd的线性复制型(RF-III)DNA、限制性内切酶R.HinHI切割得到的片段以及R.Hga切割得到的片段的差异解链图谱。根据这些结果构建了一个定位DNA上协同解链区域的物理图谱,并与遗传图谱进行了比较。