Ryan U S, Schultz D R, Ruan J W
Science. 1981 Oct 30;214(4520):557-8. doi: 10.1126/science.6270789.
Receptors for the activated third component of complement and for the Fc portion of immunoglobulin G are not expressed by apparently normal bovine pulmonary endothelial cells, but are expressed when the cells are exposed to white cell lysates or are infected with influenza or cytomegalovirus. The unmasking of these latent receptors may contribute to the pulmonary inflammatory response characteristic of, for example, anaphylaxis and to those lung diseases characterized by the deposition of immune complexes.
补体激活的第三成分受体和免疫球蛋白G的Fc段受体在外观正常的牛肺内皮细胞中不表达,但当细胞暴露于白细胞裂解物或感染流感病毒或巨细胞病毒时会表达。这些潜在受体的暴露可能导致例如过敏反应所特有的肺部炎症反应,以及那些以免疫复合物沉积为特征的肺部疾病。