Petrini B, Wasserman J, Baral E, Blomgren H, Strender L E
Acta Radiol Oncol. 1981;20(2):137-41. doi: 10.3109/02841868109130434.
Peripheral lymphocyte subpopulations were examined in 37 women with breast carcinoma who were postoperatively randomized to adjuvant local radiation therapy or cyclic treatment with 5-Fluorouracil, Methotrexate and Chlorambucil. Both T and non-T lymphocyte counts were reduced but the latter subpopulation was reduced to the highest relative extent in both groups of patients. Following radiation therapy the non-T cells repopulated more rapidly than the T cells, whereas the repopulation seemed to be the reverse in patients treated with chemotherapy.
对37例乳腺癌女性患者的外周淋巴细胞亚群进行了检查,这些患者术后被随机分为辅助局部放射治疗组或接受5-氟尿嘧啶、甲氨蝶呤和苯丁酸氮芥的循环治疗组。T淋巴细胞和非T淋巴细胞计数均减少,但在两组患者中,后一亚群减少的相对程度最高。放射治疗后,非T细胞的重新增殖比T细胞更快,而在接受化疗的患者中,重新增殖情况似乎相反。