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乳腺癌患者辅助放疗与周期性化疗的比较。I. 血液淋巴细胞亚群的变化

Adjuvant radiation therapy compared with cyclic chemotherapy in patients with mammary carcinoma. I. Changes of blood lymphocyte subpopulations.

作者信息

Petrini B, Wasserman J, Baral E, Blomgren H, Strender L E

出版信息

Acta Radiol Oncol. 1981;20(2):137-41. doi: 10.3109/02841868109130434.

DOI:10.3109/02841868109130434
PMID:6270966
Abstract

Peripheral lymphocyte subpopulations were examined in 37 women with breast carcinoma who were postoperatively randomized to adjuvant local radiation therapy or cyclic treatment with 5-Fluorouracil, Methotrexate and Chlorambucil. Both T and non-T lymphocyte counts were reduced but the latter subpopulation was reduced to the highest relative extent in both groups of patients. Following radiation therapy the non-T cells repopulated more rapidly than the T cells, whereas the repopulation seemed to be the reverse in patients treated with chemotherapy.

摘要

对37例乳腺癌女性患者的外周淋巴细胞亚群进行了检查,这些患者术后被随机分为辅助局部放射治疗组或接受5-氟尿嘧啶、甲氨蝶呤和苯丁酸氮芥的循环治疗组。T淋巴细胞和非T淋巴细胞计数均减少,但在两组患者中,后一亚群减少的相对程度最高。放射治疗后,非T细胞的重新增殖比T细胞更快,而在接受化疗的患者中,重新增殖情况似乎相反。

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Adjuvant radiation therapy compared with cyclic chemotherapy in patients with mammary carcinoma. I. Changes of blood lymphocyte subpopulations.乳腺癌患者辅助放疗与周期性化疗的比较。I. 血液淋巴细胞亚群的变化
Acta Radiol Oncol. 1981;20(2):137-41. doi: 10.3109/02841868109130434.
2
Adjuvant radiation therapy compared with cyclic chemotherapy in patients with mammary carcinoma. II. Changes of mitogen responses of blood lymphocytes.乳腺癌患者辅助放疗与周期性化疗的比较。II. 血液淋巴细胞有丝分裂原反应的变化。
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