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[实验性矽肺。II. 高温对陶瓷用石英及石英砂致纤维化作用的影响]

[Experimental silicosis. II. Effects of high temperature of fibrogenic effect of quartz and quartz sands used in ceramics].

作者信息

Gościcki J, Woźniak H, Wiecek E, Wojtczak J

出版信息

Med Pr. 1981;32(2):109-18.

PMID:6273685
Abstract

Fibrogenic effects of siliceous ceramic raw materials (quartz and quartz sand), heated at 1200 degrees C for 72 hours (conditions of ceramic products burning) have been investigated. The evaluation of fibrogenic effects has been based on wet lungs weight and hydroxyproline content in rats' lungs after an intratracheal administration of 50 mg of the test dust, during 3 and 6 months' experiment. The obtained results indicate that high temperature affects the polymorphous transformation of silica. The transformation varies, e.g. crystabillite has been found in quartz, whereas in quartz sands, quartz has been found apart from crystaballite. In the Isere quartz from Nowosolna crystalline silica content has been decreased, as compared to unheated samples. Heating does not reduce fibrogenic effects of some samples e.g. quartz sand from Biała Góra), or the activity may be increased (e.g. quartz sand from Winiary), or is not changed (quartz from Austria). The tendency of changes in biological aggressiveness of siliceous dusts subjected to high temperature cannot be foreseen, as those changes depend on different factos, among others on the content of various impurities.

摘要

研究了硅质陶瓷原料(石英和石英砂)在1200摄氏度下加热72小时(陶瓷制品烧制条件)后的致纤维化作用。致纤维化作用的评估基于在3个月和6个月的实验期间,对大鼠气管内给予50毫克受试粉尘后,大鼠肺湿重和肺中羟脯氨酸含量。所得结果表明,高温影响二氧化硅的多晶型转变。转变情况各不相同,例如在石英中发现了方石英,而在石英砂中,除方石英外还发现了石英。与未加热的样品相比,来自诺沃索尔纳的伊泽尔石英中的结晶二氧化硅含量有所降低。加热不会降低某些样品(如比亚瓦戈拉的石英砂)的致纤维化作用,或者活性可能会增加(如维尼阿里的石英砂),或者没有变化(奥地利的石英)。由于这些变化取决于不同因素,尤其是各种杂质的含量,因此无法预见高温处理后的硅质粉尘生物侵袭性的变化趋势。

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