Brayer G D, McPherson A
J Biol Chem. 1982 Apr 10;257(7):3359-61.
Crystals suitable for three-dimensional x-ray diffraction analysis have been reproducibly grown of both pancreatic ribonuclease A and B, and also of their complexes with deoxy-(pA)4 and deoxy-(pA)6. The crystals, all of which are grown from polyethylene glycol 4000 at low ionic strength, diffract to high resolution and would seem to provide another opportunity for the direct visualization of a protein-nucleic acid interaction.
适合进行三维X射线衍射分析的晶体已被反复培养出来，包括胰腺核糖核酸酶A和B，以及它们与脱氧（pA）4和脱氧（pA）6的复合物。所有这些晶体都是在低离子强度下从聚乙二醇4000中生长出来的，它们能衍射到高分辨率，似乎为直接观察蛋白质-核酸相互作用提供了另一个机会。
