Carl M, Kantor R J, Webster H M, Fields H A, Maynard J E
J Med Virol. 1982;9(2):125-9. doi: 10.1002/jmv.1890090207.
A study was carried out to determine whether hepatitis A virus (HAV) can be detected in the stools of patients hospitalized for HAV infection. Acute phase samples of whole blood and stool, as well as completed questionnaires, were obtained from 31 patients hospitalized at any of 13 hospitals in the Phoenix metropolitan area. Blood specimens were tested for hepatitis B surface antigen (HBsAg), IgG antibody to HAV (IgG anti-HAV), and IgM antibody to HAV (IgM anti-HAV). Stools were tested for HAV by radioimmunoassay. Five patients (16.1%) had acute hepatitis B, five (16.1%) had acute non-A/non-B hepatitis, and 21 (67.7%) had acute hepatitis A. Of these 21 patients with acute hepatitis A, 11 (52.4%) were found to have HAV in their stools. These results confirm the potential for infectivity of stools of patients hospitalized for hepatitis A and emphasizes the need for caution when dealing with such stools.
开展了一项研究，以确定甲型肝炎病毒（HAV）是否能在因甲型肝炎病毒感染而住院的患者粪便中检测到。从凤凰城大都市区13家医院中任何一家住院的31名患者处获取了急性期全血和粪便样本以及完整问卷。对血液标本进行了乙型肝炎表面抗原（HBsAg）、甲型肝炎病毒IgG抗体（IgG抗-HAV）和甲型肝炎病毒IgM抗体（IgM抗-HAV）检测。通过放射免疫测定法对粪便进行甲型肝炎病毒检测。5名患者（16.1%）患有急性乙型肝炎，5名患者（16.1%）患有急性非甲非乙型肝炎，21名患者（67.7%）患有急性甲型肝炎。在这21名急性甲型肝炎患者中，11名（52.4%）被发现粪便中含有甲型肝炎病毒。这些结果证实了因甲型肝炎住院患者粪便具有传染性的可能性，并强调处理此类粪便时需要谨慎。
