胆囊收缩素对大鼠促甲状腺激素释放激素（TRH）诱导的5-羟色胺增强作用的影响。

Effect of cholecystokinin on thyrotropin releasing hormone (TRH)-induced serotonin potentiation in rats.

作者信息

Itoh S, Katsuura G

出版信息

Jpn J Physiol. 1982;32(1):145-8. doi: 10.2170/jjphysiol.32.145.

DOI:10.2170/jjphysiol.32.145

Abstract

Cholecystokinin octapeptide (CCK-8) did not affect the behavioral syndrome of rats treated with pargyline and 5-hydroxytryptamine, while TRH produced a marked behavioral excitation under the same condition. However, the serotonin-potentiating effect of TRH was apparently suppressed by simultaneous administration of CCK-8.

摘要

胆囊收缩素八肽（CCK - 8）对用优降宁和5 - 羟色胺处理的大鼠的行为综合征没有影响，而促甲状腺激素释放激素（TRH）在相同条件下产生明显的行为兴奋。然而，同时给予CCK - 8可明显抑制TRH的5 - 羟色胺增强作用。