Hisano S, Kawano H, Nishiyama T, Daikoku S
Cell Tissue Res. 1982;224(2):303-14. doi: 10.1007/BF00216875.
In the preinfundibular portion of male rat hypothalamus, the arcuate-median eminence region was examined after staining with anti-porcine ACTH 1-39 serum. In several cases, anti-beta-endorphin serum was also employed. Both sera stain the same cell bodies. The cell bodies of the immunoreactive neurons are scattered in the subependymal layer, arcuate nucleus and lateral tuberal region. Fibers originating from these cell bodies are distributed extensively throughout these regions. They make synaptic contacts on immunonegative fibers in the arcuate nuclei, or terminate directly in the perivascular space in the internal layer of the median eminence. The findings suggest that the ACTH/beta-endorphin neuronal system may serve neuronally and humorally as an intrahypothalamic constituent of the hypothalamic pituitary regulation system.
在雄性大鼠下丘脑漏斗前部，用抗猪促肾上腺皮质激素1 - 39血清染色后，对弓状 - 正中隆起区域进行了检查。在一些情况下，还使用了抗β - 内啡肽血清。两种血清都能使相同的细胞体染色。免疫反应性神经元的细胞体散布在室管膜下层、弓状核和外侧结节区域。源自这些细胞体的纤维广泛分布于这些区域。它们在弓状核的免疫阴性纤维上形成突触联系，或直接终止于正中隆起内层的血管周围间隙。这些发现表明，促肾上腺皮质激素/β - 内啡肽神经元系统可能在神经和体液方面作为下丘脑 - 垂体调节系统的下丘脑内成分发挥作用。
