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大鼠下丘脑弓状核及周围区域中β-内啡肽/β-促脂素样免疫反应性神经元的光镜和电镜免疫细胞化学研究

Light and electron microscopic immunocytochemistry of beta-endorphin/beta-LPH-like immunoreactive neurons in the arcuate nucleus and surrounding areas of the rat hypothalamus.

作者信息

Ibata Y, Kawakami F, Okamura H, Obata-Tsuto H L, Morimoto N, Zimmerman E A

出版信息

Brain Res. 1985 Aug 26;341(2):233-42. doi: 10.1016/0006-8993(85)91062-5.

DOI:10.1016/0006-8993(85)91062-5
PMID:2931156
Abstract

beta-Endorphin/beta-LPH-like immunoreactive neurons in the hypothalamic arcuate nucleus and its surrounding areas were visualized by light and electron microscopic immunocytochemistry. Immunoreactive processes were found in the vicinity of the pia mater, in the lateral part of the external layer of the median eminence and near the lateral wall of the third ventricle. Neuronal perikarya contained immunoreactive dense granules as well as developed cell organellae. They received neuronal inputs from other neurons through axoplasmic and axodendritic synapses. Immunoreactive neuronal processes containing dense granules and mitochondria were found as preterminal elements on non-immunoreactive neuronal soma and dendrites. Immunoreactive processes also make intimate contact with capillaries in the arcuate nucleus near the median eminence.

摘要

通过光镜和电镜免疫细胞化学方法观察到下丘脑弓状核及其周围区域中β-内啡肽/β-促脂解素样免疫反应性神经元。在软脑膜附近、正中隆起外层的外侧部分以及第三脑室侧壁附近发现了免疫反应性突起。神经元胞体含有免疫反应性致密颗粒以及发达的细胞器。它们通过轴浆突触和轴树突触接受来自其他神经元的神经输入。在非免疫反应性神经元胞体和树突上发现含有致密颗粒和线粒体的免疫反应性神经元突起作为终末前成分。免疫反应性突起还与正中隆起附近弓状核内的毛细血管紧密接触。

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