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尼日利亚健康人群中的甲型肝炎病毒抗体。

Antibody to hepatitis A virus in healthy Nigerians.

作者信息

Ayoola E A

出版信息

J Natl Med Assoc. 1982 May;74(5):465-8.

Abstract

Two hundred and fifty Nigerians (175 male and 75 female), whose ages ranged from 5 to 70 years, were surveyed for the presence of antibody to hepatitis A virus (anti-HAV). The prevalence was determined to be 82 percent. The rates were highest in blood donors (90 percent) and hospital workers (91.4 percent) and lowest in children under the age of 10 (25 percent). The prevalence rates were not related to socioeconomic groups, previous exposure, jaundice, or sex. The study confirms that HAV infection is endemic in Nigeria and that most infections are subclinical and occur early in life. Acute hepatitis in a Nigerian adult may therefore not be due to HAV.

摘要

对250名年龄在5至70岁之间的尼日利亚人(175名男性和75名女性)进行了甲型肝炎病毒抗体(抗-HAV)检测。检测发现患病率为82%。献血者(90%)和医院工作人员(91.4%)的患病率最高,10岁以下儿童的患病率最低(25%)。患病率与社会经济群体、既往接触史、黄疸或性别无关。该研究证实,甲型肝炎病毒感染在尼日利亚呈地方性流行,且大多数感染为亚临床感染并发生在生命早期。因此,尼日利亚成年人的急性肝炎可能并非由甲型肝炎病毒引起。

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