Goldsbrough P B, Ellis T H, Lomonossoff G P
Nucleic Acids Res. 1982 Aug 11;10(15):4501-14. doi: 10.1093/nar/10.15.4501.
The complete sequence of the flax 5S DNA repeat is presented. Length heterogeneity is the consequence of the presence or absence of a single direct repeat and the majority of single base changes are transition mutations. No sequence variation has been found in the coding sequence. The extent of methylation of cytosines has been measured at one location in the gene and one in the spacer. The relationship between the observed sequence heterogeneity and the level of methylation is discussed in the context of the operation of a correction mechanism.
本文展示了亚麻5S DNA重复序列的完整序列。长度异质性是由于单个直接重复序列的存在或缺失导致的，并且大多数单碱基变化是转换突变。在编码序列中未发现序列变异。已在基因中的一个位置和间隔区中的一个位置测量了胞嘧啶的甲基化程度。在一种校正机制的运作背景下讨论了观察到的序列异质性与甲基化水平之间的关系。
