Shanley J D
J Gen Virol. 1982 Nov;63 (Pt 1):251-4. doi: 10.1099/0022-1317-63-1-251.
Ultraviolet irradiation of murine cytomegalovirus (MCMV) caused a rapid dose-related decline in virus infectivity, manifested by virus antigen induction, and in virus production as measured by plaque formation and infectious centre assay. The virus survival curve was multi-component, suggesting host cell-assisted reactivation. Multiplicity reactivation and photoreactivation of MCMV were not observed in these experiments. Productive infection was more sensitive to u.v. irradiation than was virus antigen production, indicating differential inactivation of virus functions. The effects of u.v. irradiation were similar in most respects to those reported for human cytomegalovirus.
对鼠巨细胞病毒（MCMV）进行紫外线照射会导致病毒感染力迅速出现与剂量相关的下降，这表现为病毒抗原诱导以及通过蚀斑形成和感染中心测定法所测量的病毒产生量下降。病毒存活曲线呈多组分，提示存在宿主细胞辅助再激活。在这些实验中未观察到MCMV的多重复活和光复活。与病毒抗原产生相比，增殖性感染对紫外线照射更敏感，表明病毒功能的失活存在差异。紫外线照射的影响在大多数方面与针对人巨细胞病毒所报道的影响相似。
