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细菌糖原的生物合成。根据glg C基因的核苷酸序列推导的大肠杆菌ADP - 葡萄糖合成酶的一级结构。

Biosynthesis of bacterial glycogen. Primary structure of Escherichia coli ADP-glucose synthetase as deduced from the nucleotide sequence of the glg C gene.

作者信息

Baecker P A, Furlong C E, Preiss J

出版信息

J Biol Chem. 1983 Apr 25;258(8):5084-8.

PMID:6300111
Abstract

The nucleotide sequence of the glg C gene of Escherichia coli K12, coding for ADP-glucose synthetase, has been determined. The structural gene consists of 1293 base pairs, which specify a protein of 431 amino acids. The amino acid sequence deduced from the DNA sequence is consistent with the known NH2-terminal amino acid sequence and the amino acid composition of ADP-glucose synthetase. The translation start of the structural gene of glycogen synthase, glg A, starts immediately after termination of the glg C gene.

摘要

已确定大肠杆菌K12编码ADP - 葡萄糖合成酶的glg C基因的核苷酸序列。该结构基因由1293个碱基对组成，其编码一个含有431个氨基酸的蛋白质。从DNA序列推导的氨基酸序列与已知的ADP - 葡萄糖合成酶的氨基末端氨基酸序列和氨基酸组成一致。糖原合酶的结构基因glg A的翻译起始于glg C基因终止后立即开始。

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