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Genetic relatedness and colinearity of genomes of equine herpesvirus types 1 and 3.马疱疹病毒1型和3型基因组的遗传相关性与共线性
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引用本文的文献

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2
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Arch Virol. 1989;104(1-2):77-86. doi: 10.1007/BF01313809.
3
Asinine herpesvirus genomes: comparison with those of the equine herpesviruses.驴疱疹病毒基因组：与马疱疹病毒基因组的比较。
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本文引用的文献

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SOME PHYSICOCHEMICAL CHARACTERISTICS OF EQUINE ABORTION VIRUS NUCLEIC ACID.马流产病毒核酸的一些物理化学特性
Virology. 1965 Jul;26:394-405. doi: 10.1016/0042-6822(65)90003-6.
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NUCLEOTIDE COMPOSITION OF SHORT SEGMENTS OF DNA MOLECULES.DNA分子短片段的核苷酸组成
J Mol Biol. 1965 Feb;11:223-37. doi: 10.1016/s0022-2836(65)80053-5.
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SEROLOGICAL COMPARISON OF THE HERPES VIRUSES.疱疹病毒的血清学比较
Br J Exp Pathol. 1964 Apr;45(2):135-41.
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Properties of the genome of equine herpesvirus type 3.马疱疹病毒3型基因组的特性
Virology. 1982 Jul 15;120(1):18-32. doi: 10.1016/0042-6822(82)90003-4.
5
Electron microscopic study of equine herpesvirus type 1 DNA.马疱疹病毒1型DNA的电子显微镜研究
J Virol. 1982 Apr;42(1):297-300. doi: 10.1128/JVI.42.1.297-300.1982.
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Structure of the genome of equine herpesvirus type 1.1型马疱疹病毒的基因组结构
Virology. 1981 Nov;115(1):97-114. doi: 10.1016/0042-6822(81)90092-1.
7
Equine cytomegalovirus: cultural characteristics and properties of viral DNA.马巨细胞病毒：病毒DNA的培养特性及性质
Virology. 1981 Feb;109(1):106-19. doi: 10.1016/0042-6822(81)90475-x.
8
Oncogenic transformation by equine herpesviruses (EHV). I. Properties of hamster embryo cells transformed by ultraviolet-irradiated EHV-1.马疱疹病毒（EHV）的致癌转化。I. 经紫外线照射的EHV-1转化的仓鼠胚胎细胞的特性。
Virology. 1980 Mar;101(2):335-62. doi: 10.1016/0042-6822(80)90449-3.
9
Chronic production of defective-interfering particles by hamster embryo cultures of herpesvirus persistently infected and oncogenically transformed cells.由疱疹病毒持续感染和致癌转化细胞的仓鼠胚胎培养物长期产生缺陷干扰颗粒。
J Gen Virol. 1982 May;60(Pt 1):1-14. doi: 10.1099/0022-1317-60-1-1.
10
Kinetics of cellular and viral DNA synthesis in equine abortion (herpes) virus infection of L-M cells.马流产（疱疹）病毒感染L-M细胞时细胞和病毒DNA合成的动力学
Virology. 1968 Sep;36(1):104-14. doi: 10.1016/0042-6822(68)90120-7.

1型、2型和3型马疱疹病毒基因组的遗传相关性。

Genetic relatedness of the genomes of equine herpesvirus types 1, 2, and 3.

作者信息

Staczek J, Atherton S S, O'Callaghan D J

出版信息

J Virol. 1983 Feb;45(2):855-8. doi: 10.1128/JVI.45.2.855-858.1983.

DOI:10.1128/JVI.45.2.855-858.1983
PMID:6300438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC256479/
Abstract

Genomic DNAs of equine herpesvirus type 1 (EHV-1), EHV-2 (equine cytomegalovirus), and EHV-3 were examined by reassociation kinetic and thermal denaturation analyses to determine the extent and degree of homology among the three viral DNAs. Results of reassociation analyses indicated a limited homology among the three EHV genomes. Homologous DNA sequences equivalent to 1.8 to 3.7 megadaltons between EHV-1 and equine cytomegalovirus, 7.6 to 8.2 megadaltons between EHV-1 and EHV-3, and 1.3 to 1.9 megadaltons between equine cytomegalovirus and EHV-3 were detected. Examination by thermal denaturation of the DNA homoduplexes and heteroduplexes formed during reassociation revealed a high degree of base pairing within the duplexes, suggesting that closely related sequences may be conserved among the genomes of EHV.

摘要

通过重缔合动力学和热变性分析对1型马疱疹病毒（EHV-1）、EHV-2（马巨细胞病毒）和EHV-3的基因组DNA进行了检测，以确定三种病毒DNA之间同源性的范围和程度。重缔合分析结果表明三种EHV基因组之间存在有限的同源性。检测到EHV-1与马巨细胞病毒之间相当于1.8至3.7兆道尔顿的同源DNA序列，EHV-1与EHV-3之间为7.6至8.2兆道尔顿，马巨细胞病毒与EHV-3之间为1.3至1.9兆道尔顿。对重缔合过程中形成的DNA同型双链体和异型双链体进行热变性检测，结果显示双链体内碱基配对程度很高，这表明EHV基因组之间可能存在密切相关的保守序列。