分次X射线照射和辐射性白血病病毒诱导白血病均涉及2号染色体H-30-A区段中的基因座。
Induction of leukemia by both fractionated x-irradiation and radiation leukemia virus involves loci in the chromosome 2 segment H-30-A.
作者信息
Meruelo D, Offer M, Rossomando A
出版信息
Proc Natl Acad Sci U S A. 1983 Jan;80(2):462-6. doi: 10.1073/pnas.80.2.462.
Abstract
A common link between the induction of leukemia by (i) fractionated doses of x-irradiation and (ii) radiation leukemia virus in mice may be established by the observation that the segment of chromosome 2 between the loci for the minor histocompatibility antigen H-30 and color coat agouti (H-30-A) includes distinct loci involved in susceptibility to leukemogenesis induced by factors i and ii.
摘要
小鼠中（i）分次剂量的X射线照射和（ii）辐射白血病病毒诱发白血病之间的一个共同联系，可能可通过以下观察结果得以确立：在次要组织相容性抗原H - 30和毛色刺鼠（H - 30 - A）基因座之间的2号染色体片段，包含参与对由因素i和ii诱发白血病易感性的不同基因座。
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