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亲胸腺性、嗜亲性和嗜异性辐射白血病病毒分离株的致白血病活性。

Leukemogenic activity of thymotropic, ecotropic, and xenotropic radiation leukemia virus isolates.

作者信息

Haas M

出版信息

J Virol. 1978 Mar;25(3):705-9. doi: 10.1128/JVI.25.3.705-709.1978.

Abstract

Thymotropic, ecotropic, and xenotropic oncoviruses were isolated from the C57BL/6 mouse radiation leukemia system and were propagated in culture. The purified viruses were inoculated singly and in various combinations into groups of mice, and leukemia incidence was determined. Only the thymotropic virus was leukemogenic in vivo.

摘要

从C57BL/6小鼠辐射白血病系统中分离出嗜胸腺性、嗜亲性和嗜异性肿瘤病毒,并在培养物中进行增殖。将纯化后的病毒单独及以各种组合接种到多组小鼠体内,然后测定白血病发病率。只有嗜胸腺性病毒在体内具有致白血病作用。

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