Gurwith M, Wenman W, Gurwith D, Brunton J, Feltham S, Greenberg H
J Infect Dis. 1983 Apr;147(4):685-92. doi: 10.1093/infdis/147.4.685.
Diarrhea among neonates and their siblings was studied in 98 families living in Winnipeg, Manitoba, and in 31 native Indian families and in 15 Inuit (Eskimo) families living in isolated settlements in northern Canada. The rate of infection due to rotavirus in neonates was significantly higher and infection occurred more often in the first six months of life in the northern communities (range, 0.36 in Winnipeg to 1.07 in Eskimo Point). No protective effect of breast-feeding was discerned, since infection due to rotavirus occurred more frequently and earliest in neonatal life in Eskimo Point, the community with the highest rate of breast-feeding. In contrast, infection due to Norwalk virus was most common among the neonates of Berens River (0.15 infections per child per year), the only community with relatively unsafe water supplies. Infection due to rotavirus appears to be more frequent in the far North, whereas infection due to Norwalk virus appears to be related more to inadequate sanitation.
对居住在马尼托巴省温尼伯市的98个家庭、31个印第安原住民家庭以及居住在加拿大北部偏远定居点的15个因纽特(爱斯基摩)家庭中的新生儿及其兄弟姐妹的腹泻情况进行了研究。轮状病毒导致的新生儿感染率在北部社区显著更高,且感染更多发生在生命的前六个月(范围从温尼伯的0.36到爱斯基摩角的1.07)。未发现母乳喂养的保护作用,因为在母乳喂养率最高的爱斯基摩角社区,轮状病毒感染在新生儿期发生得更频繁且更早。相比之下,诺沃克病毒感染在贝伦斯河的新生儿中最为常见(每年每个儿童感染0.15次),该社区是唯一供水相对不安全的社区。轮状病毒感染在极北地区似乎更频繁,而诺沃克病毒感染似乎更多与卫生条件不足有关。