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周围神经病变的快速筛查:使用Optacon的现场研究。

Rapid screening for peripheral neuropathy: a field study with the Optacon.

作者信息

Arezzo J C, Schaumburg H H, Petersen C A

出版信息

Neurology. 1983 May;33(5):626-9. doi: 10.1212/wnl.33.5.626.

DOI:10.1212/wnl.33.5.626
PMID:6302556
Abstract

The modified Optacon, a simple battery-powered device that measures fingertip vibration sensation, was used by para-professionals to screen 257 acrylamide-exposed individuals. Consistent data were obtained on repeated testing of individuals, and there was an age-related linear decrease in vibration sensitivity within the population. Subclinical peripheral neuropathy was detected in two individuals, one acrylamide-related and the other nutritional-alcoholic. This study establishes the use of the modified Optacon as a screening device for some types of peripheral nerve dysfunction.

摘要

改良型Optacon是一种简单的电池供电设备,用于测量指尖振动感觉,准专业人员用它对257名接触丙烯酰胺的个体进行筛查。对个体进行重复测试时获得了一致的数据,并且在该人群中振动敏感性存在与年龄相关的线性下降。在两名个体中检测到亚临床周围神经病变,其中一例与丙烯酰胺有关,另一例与营养性酒精中毒有关。本研究确立了改良型Optacon作为某些类型周围神经功能障碍筛查设备的用途。

相似文献

1
Rapid screening for peripheral neuropathy: a field study with the Optacon.周围神经病变的快速筛查:使用Optacon的现场研究。
Neurology. 1983 May;33(5):626-9. doi: 10.1212/wnl.33.5.626.
2
The use of the optacon as a screening device. A new technique for detecting sensory loss in individuals exposed to neurotoxins.
J Occup Med. 1980 Jul;22(7):461-4.
3
Quantitative measurements of vibration threshold in healthy adults and acrylamide workers.健康成年人与丙烯酰胺作业工人振动阈值的定量测量
Int Arch Occup Environ Health. 1993;65(1):53-6. doi: 10.1007/BF00586059.
4
Nervous system degeneration produced by acrylamide monomer.丙烯酰胺单体导致的神经系统退化。
Environ Health Perspect. 1975 Jun;11:129-33. doi: 10.1289/ehp.7511129.
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[Biothesiometry in the diagnosis of peripheral neuropathies].[生物感觉定量测定法在周围神经病变诊断中的应用]
Cas Lek Cesk. 2002 Apr 12;141(7):223-5.
6
Relationships between biomarkers of exposure and neurological effects in a group of workers exposed to acrylamide.
Toxicol Appl Pharmacol. 1994 Jun;126(2):361-71. doi: 10.1006/taap.1994.1127.
7
Screening occupational populations for asymptomatic or early peripheral neuropathy.对职业人群进行无症状或早期周围神经病变的筛查。
J Occup Med. 1986 Oct;28(10):975-86. doi: 10.1097/00043764-198610000-00016.
8
Vibration sensitivity as a parameter for detecting peripheral neuropathy. I. Results in healthy workers.振动觉敏感性作为检测周围神经病变的一个参数。I. 健康工人的结果
Int Arch Occup Environ Health. 1986;58(4):287-99. doi: 10.1007/BF00377886.
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Acrylamide monomer and peripheral neuropathy in chemical workers.化学工业工人中的丙烯酰胺单体与周围神经病变
Am J Ind Med. 1992;21(2):217-22. doi: 10.1002/ajim.4700210211.
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Acrylamide neuropathy in a South African factory: an epidemiologic investigation.南非一家工厂的丙烯酰胺神经病变:一项流行病学调查。
Am J Ind Med. 1991;19(4):487-93. doi: 10.1002/ajim.4700190406.

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Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes, and demonstration of axo-glial dysjunction in human diabetic neuropathy.胰岛素依赖型和非胰岛素依赖型糖尿病中神经病变的组织病理学异质性,以及人类糖尿病性神经病变中轴突-神经胶质分离的证明。
J Clin Invest. 1988 Feb;81(2):349-64. doi: 10.1172/JCI113327.
2
Vibration sensitivity as a parameter for detecting peripheral neuropathy. I. Results in healthy workers.振动觉敏感性作为检测周围神经病变的一个参数。I. 健康工人的结果
Int Arch Occup Environ Health. 1986;58(4):287-99. doi: 10.1007/BF00377886.
3
The influence of spatial contrast on the frequency-dependent nature of vibration sensitivity.
Percept Psychophys. 1990 Nov;48(5):431-5. doi: 10.3758/bf03211586.
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Large and small fibre type sensory dysfunction in patients with cancer.癌症患者的大小纤维型感觉功能障碍
J Neurol Neurosurg Psychiatry. 1991 Aug;54(8):706-9. doi: 10.1136/jnnp.54.8.706.