Ohkawa T, Ebisuno S, Kitagawa M, Morimoto S, Miyazaki Y
J Urol. 1983 May;129(5):1009-11. doi: 10.1016/s0022-5347(17)52512-4.
We report on the efficacy of rice bran in hypercalciuric patients with urinary calculous disease. After the administration of defatted rice bran at a dosage of 20 gm. daily for 4 weeks urinary calcium excretion was reduced significantly from 402 plus or minus 102 to 291 plus or minus 123 mg. per 24 hours. In 6 patients who showed a reduction of urinary calcium excretion an increase in urinary calcium excretion was observed 4 weeks after stopping the administration. All 7 patients who previously received defatted rice bran were given processed or rice bran free of phytin at a dosage of 20 gm. daily. The value of urinary calcium excretion increased again during the administration of processed rice bran but was less marked than that of the preceding 6 patients. Although it is interesting to debate whether the influence of rice bran on the urinary calcium excretion depends on the action of phytin or of other constituents defatted rice bran should be effective in reducing urinary excretion of calcium. These results would come up to the expectations of the patients with recurrent urinary calculous disease.
我们报告了米糠对患有尿路结石疾病的高钙尿症患者的疗效。给予脱脂米糠，剂量为每日20克，持续4周后，尿钙排泄量从每24小时402±102毫克显著降至291±123毫克。在6例尿钙排泄量减少的患者中，停药4周后观察到尿钙排泄量增加。所有7例先前接受脱脂米糠的患者均给予加工过的或不含肌醇六磷酸的米糠，剂量为每日20克。在给予加工米糠期间，尿钙排泄值再次升高，但不如前6例患者明显。尽管关于米糠对尿钙排泄的影响是取决于肌醇六磷酸还是其他成分的作用存在争议，但脱脂米糠在减少尿钙排泄方面应该是有效的。这些结果符合复发性尿路结石疾病患者的期望。
