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多头绒泡菌26S rRNA基因的完整核苷酸序列:其在基因进化中的意义

Complete nucleotide sequence of the 26S rRNA gene of Physarum polycephalum: its significance in gene evolution.

作者信息

Otsuka T, Nomiyama H, Yoshida H, Kukita T, Kuhara S, Sakaki Y

出版信息

Proc Natl Acad Sci U S A. 1983 Jun;80(11):3163-7. doi: 10.1073/pnas.80.11.3163.

Abstract

The complete nucleotide sequences of the 5.8S and 26S rRNA genes of Physarum polycephalum and the transcribed spacer between them were determined. Comparison of the sequences with those of the Escherichia coli 23S rRNA and yeast 26S rRNA genes showed that there are 16 highly homologous regions in the sequences of Physarum and E. coli and that eukaryotes have some eukaryote-specific extra sequences. The sequence immediately following the 5.8S-like region of E. coli 23S rRNA was found to be highly homologous to the 5' terminus of Physarum 26S rRNA, indicating that the eukaryote-specific 5.8S rRNA gene is derived from the 5'-terminal region of the prokaryote large rRNA gene.

摘要

测定了多头绒泡菌5.8S和26S rRNA基因及其转录间隔区的完整核苷酸序列。将这些序列与大肠杆菌23S rRNA和酵母26S rRNA基因的序列进行比较,结果表明,绒泡菌和大肠杆菌的序列中有16个高度同源区域,并且真核生物有一些真核生物特有的额外序列。发现紧跟在大肠杆菌23S rRNA的5.8S样区域之后的序列与多头绒泡菌26S rRNA的5'末端高度同源,这表明真核生物特有的5.8S rRNA基因源自原核生物大rRNA基因的5'-末端区域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec48/394000/37d665d6e9bd/pnas00637-0030-a.jpg

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