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甲状腺分泌三碘甲状腺原氨酸(毒性)腺瘤:光镜和电镜特征

Triiodothyronine-secreting (toxic) adenoma of the thyroid gland: light and electron microscopic characteristics.

作者信息

Panke T W, Croxson M S, Parker J W, Carriere D P, Rosoff L, Warner N E

出版信息

Cancer. 1978 Feb;41(2):528-37. doi: 10.1002/1097-0142(197802)41:2<528::aid-cncr2820410220>3.0.co;2-v.

DOI:10.1002/1097-0142(197802)41:2<528::aid-cncr2820410220>3.0.co;2-v
PMID:630535
Abstract

A patient with thyrotoxicosis due to a triiodothyronine (T3)-secreting autonomous adenoma is described. The histmorphology of the neoplasms was similar to other neoplasms previously reported. Ultrastructural features of the adenoma are compatible with a very actively secreting follicular cell and are best compared with the ultrastructure of a diffuse toxic goiter. Distinctive features that separate toxic adenomas from various thyroid carcinomas and normal thyroid parenchyma are discussed.

摘要

本文描述了一名因分泌三碘甲状腺原氨酸(T3)的自主性腺瘤导致甲状腺毒症的患者。该肿瘤的组织形态学与先前报道的其他肿瘤相似。腺瘤的超微结构特征与分泌非常活跃的滤泡细胞相符,与弥漫性毒性甲状腺肿的超微结构最为相似。文中讨论了将毒性腺瘤与各种甲状腺癌及正常甲状腺实质区分开来的独特特征。

相似文献

1
Triiodothyronine-secreting (toxic) adenoma of the thyroid gland: light and electron microscopic characteristics.甲状腺分泌三碘甲状腺原氨酸(毒性)腺瘤:光镜和电镜特征
Cancer. 1978 Feb;41(2):528-37. doi: 10.1002/1097-0142(197802)41:2<528::aid-cncr2820410220>3.0.co;2-v.
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Coincidental thyroid papillary microcarcinoma in a patient treated for a toxic adenoma of the thyroid.甲状腺乳头状微小癌与甲状腺毒性腺瘤患者并存。
Arch Iran Med. 2011 Mar;14(2):149-51.
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Hyperfunctioning thyroid adenoma concomitant with papillary thyroid carcinoma, follicular thyroid adenoma and primary hyperparathyroidism.
Endocr J. 1998 Feb;45(1):61-7. doi: 10.1507/endocrj.45.61.
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Hürthle-cell lesions of the thyroid: a combined study using transmission electron microscopy, scanning electron microscopy, and immunocytochemistry.
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Follicular reconstruction and hormone production by human adenomatous goiter cells in culture.培养的人腺瘤性甲状腺肿细胞的滤泡重建与激素产生
Tohoku J Exp Med. 1982 Mar;136(3):285-90. doi: 10.1620/tjem.136.285.
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Surface features in human thyroid disorders. A scanning electron microscopic study of ninety five cases.
J Submicrosc Cytol. 1982 Jan;14(1):187-202.
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Transient thyrotoxicosis associated with infarction of a large thyroid adenoma.与大型甲状腺腺瘤梗死相关的短暂性甲状腺毒症
Endocrinol Jpn. 1987 Oct;34(5):779-84. doi: 10.1507/endocrj1954.34.779.
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The fine structure of follicular thyroid adenomas.滤泡性甲状腺腺瘤的精细结构。
Am J Clin Pathol. 1982 Sep;78(3):299-310. doi: 10.1093/ajcp/78.3.299.
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The significance of paravacuolar granules of the thyroid. A histologic, cytologic and ultrastructural study.甲状腺旁泡状颗粒的意义。一项组织学、细胞学及超微结构研究。
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[Serum concentration of triiodothyronine in autonomous thyroid gland adenoma].[自主性甲状腺腺瘤患者血清三碘甲状腺原氨酸浓度]
Acta Med Austriaca. 1975;2(5):190-3.

引用本文的文献

1
Simultaneous detection of thyroglobulin (Tg), thyroxine (T4), and Triiodothyronine (T3) in nontoxic thyroid tumors by the immunoperoxidase method.采用免疫过氧化物酶法同时检测非毒性甲状腺肿瘤中的甲状腺球蛋白(Tg)、甲状腺素(T4)和三碘甲状腺原氨酸(T3)。
Am J Pathol. 1982 Jul;108(1):39-49.