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灵长类动物中心的自然和实验性猿猴巨细胞病毒感染

Natural and experimental simian cytomegalovirus infections at a primate center.

作者信息

Swack N S, Hsiung G D

出版信息

J Med Primatol. 1982;11(3):169-77.

PMID:6306240
Abstract

Simian cytomegalovirus infections were studied in captive, naturally infected primates and in experimentally infected rhesus monkeys. Neutralizing antibody to simian cytomegalovirus was prevalent in selected species of Old World Monkeys. Naturally infected, rhesus monkeys shed virus in their urine during the entire two-year period of study. Similarly, experimentally infected rhesus monkeys showed neutralizing antibody and viruria for more than two years. The indirect fluorescent antibody procedure was found more sensitive than the neutralization antibody technique but appeared less specific for antibody to cytomegalovirus strains.

摘要

在圈养的自然感染灵长类动物和实验感染的恒河猴中研究了猴巨细胞病毒感染。抗猴巨细胞病毒的中和抗体在旧世界猴的某些选定物种中普遍存在。在整个两年的研究期间,自然感染的恒河猴尿液中排出病毒。同样,实验感染的恒河猴在两年多的时间里都表现出中和抗体和病毒尿。发现间接荧光抗体法比中和抗体技术更敏感,但对巨细胞病毒株抗体的特异性似乎较低。

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