冠状病毒呼吸道感染的流行病学
Epidemiology of coronavirus respiratory infections.
作者信息
Isaacs D, Flowers D, Clarke J R, Valman H B, MacNaughton M R
出版信息
Arch Dis Child. 1983 Jul;58(7):500-3. doi: 10.1136/adc.58.7.500.
Abstract
Human coronaviruses were found by enzyme linked immunosorbent assay in upper respiratory tract secretions taken during 30% of 108 acute respiratory infections experienced by 30 children under age 6 years with recurrent respiratory infections (index group), and during 29% of 51 acute infections experienced by their siblings. Lower respiratory tract infection--predominantly wheezy bronchitis--occurred in 30% of the index children's coronavirus positive infections but in none of their siblings' infections. Reinfections were common. Two peaks of infection were seen each year in the late autumn/early winter and in the early summer.
摘要
通过酶联免疫吸附测定法，在30名患有反复呼吸道感染的6岁以下儿童（索引组）经历的108次急性呼吸道感染中的30%期间采集的上呼吸道分泌物中发现了人冠状病毒，在其兄弟姐妹经历的51次急性感染中的29%期间也发现了该病毒。下呼吸道感染——主要是喘息性支气管炎——发生在索引组儿童冠状病毒阳性感染的30%中，但在其兄弟姐妹的感染中均未发生。再次感染很常见。每年在秋末/初冬和初夏出现两个感染高峰。
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