Muhm J R, Miller W E, Fontana R S, Sanderson D R, Uhlenhopp M A
Radiology. 1983 Sep;148(3):609-15. doi: 10.1148/radiology.148.3.6308709.
Ninety-two lung cancers were detected in the Mayo Lung Project in patients undergoing chest radiography every four months for screening. Fifty patients had a peripheral nodule, 16 had a perihilar nodule, 20 had hilar or mediastinal enlargement, and six had pneumonitis. The peripheral cancers grew slowly. Ninety per cent were visible in retrospect for months or even years. Despite this, 70% of the peripheral cancers were classified as postsurgical American Joint Committee (AJC) Stage 1. The central cancers grew rapidly, usually presenting as hilar or mediastinal enlargements after normal findings on the previous radiograph obtained four months earlier. Most were classified as AJC Stage 3 tumors.
在梅奥肺癌项目中，对每四个月接受一次胸部X光筛查的患者进行检查，共检测出92例肺癌。50例患者有外周结节，16例有肺门周围结节，20例有肺门或纵隔增宽，6例有肺炎。外周型癌症生长缓慢。90%的病例在回顾时可见数月甚至数年。尽管如此，70%的外周型癌症在手术后被归类为美国联合委员会（AJC）1期。中央型癌症生长迅速，通常在四个月前的上一次X光检查结果正常后表现为肺门或纵隔增宽。大多数被归类为AJC 3期肿瘤。
