Abbruzzese G, Gandolfo C, Loeb C
Ital J Neurol Sci. 1983 Jun;4(2):169-72. doi: 10.1007/BF02043900.
Two groups of 30 multiple sclerosis (MS) patients were randomly treated with corticotrophin (ACTH) and "bolus" 6-methylprednisolone (B/6-MP) to compare the effectiveness of the two treatments. Both ACTH and B/6-MP showed a similar effect, improving acute neurological deficits of MS patients without modifying the long term course of the disease. B/6-MP, showing prompt effectiveness and lack of side effects, may be regarded as a useful alternative to conventional treatment of MS.
两组各30名多发性硬化症（MS）患者被随机给予促肾上腺皮质激素（ACTH）和“大剂量”6-甲基泼尼松龙（B/6-MP）治疗，以比较两种治疗方法的效果。ACTH和B/6-MP均显示出相似的效果，可改善MS患者的急性神经功能缺损，而不改变疾病的长期病程。B/6-MP起效迅速且无副作用，可被视为MS传统治疗的一种有效替代方法。
