Coates A, Dillenbeck C F, McNeil D R, Kaye S B, Sims K, Fox R M, Woods R L, Milton G W, Solomon J, Tattersall M H
Eur J Cancer Clin Oncol. 1983 Nov;19(11):1633-7. doi: 10.1016/0277-5379(83)90096-2.
Linear analogue self-assessment (LASA) scales were used to measure general well-being and specific factors (mood, pain, nausea and vomiting, appetite, breathlessness, physical activity) in patients receiving therapy for malignant melanoma, small cell bronchogenic carcinoma (SCBC) or ovarian cancer. Among the patients with SCBC and melanoma, high correlations were observed between LASA scores for general well-being, mood and appetite. There was a significant relationship between performance status and LASA scores for general well-being, pain and appetite. Among patients with ovarian cancer, there was a significant association between performance status and LASA scores for general well-being, breathlessness and physical activity. Objective response category was related to change in LASA scores for pain. Changes in LASA scores during treatment reflected increased morbidity during radiotherapy in patients also receiving chemotherapy for SCBC. The LASA technique provides a convenient method for the assessment of quality of life in patients receiving cancer therapy, and potentially allows comparison of patient perception of treatment-related morbidities.
线性模拟自我评估（LASA）量表用于测量接受恶性黑色素瘤、小细胞支气管癌（SCBC）或卵巢癌治疗的患者的总体健康状况和特定因素（情绪、疼痛、恶心和呕吐、食欲、呼吸急促、身体活动）。在患有SCBC和黑色素瘤的患者中，观察到总体健康状况、情绪和食欲的LASA评分之间存在高度相关性。体能状态与总体健康状况、疼痛和食欲的LASA评分之间存在显著关系。在卵巢癌患者中，体能状态与总体健康状况、呼吸急促和身体活动的LASA评分之间存在显著关联。客观反应类别与疼痛的LASA评分变化相关。在接受SCBC化疗的患者中，治疗期间LASA评分的变化反映了放疗期间发病率的增加。LASA技术为评估接受癌症治疗患者的生活质量提供了一种便捷的方法，并有可能比较患者对与治疗相关的发病率的认知。
