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非洲爪蟾卵母细胞在电压钳制下的超极化激活氯离子电流

A hyperpolarization-activated chloride current in Xenopus laevis oocytes under voltage-clamp.

作者信息

Peres A, Bernardini G

出版信息

Pflugers Arch. 1983 Oct;399(2):157-9. doi: 10.1007/BF00663914.

DOI:10.1007/BF00663914
PMID:6316254
Abstract

Voltage-clamp experiments have been performed on ovulated Xenopus laevis oocytes. Two kinds of oocytes were studied: mature oocytes presenting the white spot due to germinal vesicle breakdown (GVBD) were found to be essentially unexcitable; oocytes without the white spot appeared to possess ionic channels which open transiently on hyperpolarization. The current is carried by chloride ions and, in Holtfreter's solution, has a reversal potential at approximately - 15 mV.

摘要

对排卵后的非洲爪蟾卵母细胞进行了电压钳实验。研究了两种卵母细胞：发现因生发泡破裂（GVBD）而出现白斑的成熟卵母细胞基本无兴奋性；没有白斑的卵母细胞似乎拥有在超极化时短暂开放的离子通道。电流由氯离子携带，在霍尔特弗雷特溶液中，其反转电位约为 -15 mV。

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A hyperpolarization-activated chloride current in Xenopus laevis oocytes under voltage-clamp.非洲爪蟾卵母细胞在电压钳制下的超极化激活氯离子电流
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Electrical membrane properties of the Xenopus laevis oocyte during progesterone-induced meiotic maturation.爪蟾卵母细胞在孕酮诱导的减数分裂成熟过程中的电膜性质。
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Two highly homologous members of the ClC chloride channel family in both rat and human kidney.大鼠和人类肾脏中ClC氯离子通道家族的两个高度同源成员。
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Molecular basis of epithelial Cl channels.上皮氯离子通道的分子基础。
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Hyperpolarization-activated chloride currents in Xenopus oocytes.非洲爪蟾卵母细胞中的超极化激活氯离子电流
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Slowly inactivating potassium channels induced in Xenopus oocytes by messenger ribonucleic acid from Torpedo brain.由电鳐大脑的信使核糖核酸在非洲爪蟾卵母细胞中诱导产生的缓慢失活钾通道。
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Voltage-activated and calcium-activated currents studied in solitary rod inner segments from the salamander retina.对蝾螈视网膜单个视杆细胞内节中的电压激活电流和钙激活电流进行了研究。
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Cholinergic and catecholaminergic receptors in the Xenopus oocyte membrane.非洲爪蟾卵母细胞膜中的胆碱能和儿茶酚胺能受体。
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