Wilson J D, Hugh T B
Aust N Z J Obstet Gynaecol. 1983 Aug;23(3):176-9. doi: 10.1111/j.1479-828x.1983.tb00570.x.
The case of a 33-year-old patient suffering from severe hypoglycaemia due to an insulinoma during the first trimester of pregnancy is reported. The diagnosis was established on clinical grounds and by the demonstration of hypoglycaemia, inappropriate hyperinsulinism and an increase in the percentage of circulating proinsulin. Dietary therapy maintained blood glucose at a satisfactory level from the 9th to the 17th gestational week. Localization of the tumour was achieved at that time by limited CT scanning with a narrow field. A 2 cm tumour was removed from the head of the pancreas and the blood sugar levels and insulin secretion returned to normal. Pregnancy proceeded normally and a healthy male infant weighing 3,880g was delivered at term. Ten months after delivery both mother and child were well.
报道了一名33岁患者在妊娠早期因胰岛素瘤而发生严重低血糖的病例。诊断基于临床依据以及低血糖、不适当的高胰岛素血症和循环中胰岛素原百分比增加的证实。饮食疗法使血糖在妊娠第9周到第17周维持在满意水平。当时通过有限的窄视野CT扫描实现了肿瘤定位。从胰头切除了一个2厘米的肿瘤，血糖水平和胰岛素分泌恢复正常。妊娠正常进行，足月分娩出一名体重3880克的健康男婴。分娩后十个月，母婴均状况良好。
