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温石棉对红细胞膜影响的自旋标记研究。

A spin label study of the effect of chrysotile asbestos on erythrocyte membranes.

作者信息

Gendek E, Bartosz G, Leyko W

出版信息

Br J Ind Med. 1984 Feb;41(1):46-50. doi: 10.1136/oem.41.1.46.

Abstract

Alterations in erythrocyte membranes caused by UICC B chrysotile asbestos fibres were studied in red cell ghosts using the spin label technique. The electron paramagnetic resonance (EPR) spectra of two sulphydryl reactive spin labels and one fatty acid spin probe in erythrocyte ghosts showed membrane protein modifications but no changes in lipid fluidity caused by the haemolytic chrysotile asbestos fibres.

摘要

利用自旋标记技术,在红细胞影中研究了国际抗癌联盟(UICC)B型温石棉纤维引起的红细胞膜变化。红细胞影中两种巯基反应性自旋标记物和一种脂肪酸自旋探针的电子顺磁共振(EPR)光谱显示,溶血温石棉纤维导致膜蛋白修饰,但脂质流动性未发生变化。

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本文引用的文献

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