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温石棉对红细胞膜影响的自旋标记研究。

A spin label study of the effect of chrysotile asbestos on erythrocyte membranes.

作者信息

Gendek E, Bartosz G, Leyko W

出版信息

Br J Ind Med. 1984 Feb;41(1):46-50. doi: 10.1136/oem.41.1.46.

DOI:10.1136/oem.41.1.46
PMID:6318801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1069315/
Abstract

Alterations in erythrocyte membranes caused by UICC B chrysotile asbestos fibres were studied in red cell ghosts using the spin label technique. The electron paramagnetic resonance (EPR) spectra of two sulphydryl reactive spin labels and one fatty acid spin probe in erythrocyte ghosts showed membrane protein modifications but no changes in lipid fluidity caused by the haemolytic chrysotile asbestos fibres.

摘要

利用自旋标记技术，在红细胞影中研究了国际抗癌联盟（UICC）B型温石棉纤维引起的红细胞膜变化。红细胞影中两种巯基反应性自旋标记物和一种脂肪酸自旋探针的电子顺磁共振（EPR）光谱显示，溶血温石棉纤维导致膜蛋白修饰，但脂质流动性未发生变化。

相似文献

1
A spin label study of the effect of chrysotile asbestos on erythrocyte membranes.温石棉对红细胞膜影响的自旋标记研究。
Br J Ind Med. 1984 Feb;41(1):46-50. doi: 10.1136/oem.41.1.46.
2
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3
Spin-labeling studies of the conformation of the Ca(2+)-regulatory protein calmodulin in solution and bound to the membrane skeleton in erythrocyte ghosts: implications to transmembrane signaling.溶液中及与红细胞血影膜骨架结合的Ca(2+)调节蛋白钙调蛋白构象的自旋标记研究：对跨膜信号传导的意义
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Biochim Biophys Acta. 1988 Jun 22;941(2):141-9. doi: 10.1016/0005-2736(88)90174-5.

引用本文的文献

1
A spin label study of the effects of asbestos, quartz, and titanium dioxide dusts on the bovine erythrocyte membrane.石棉、石英和二氧化钛粉尘对牛红细胞膜影响的自旋标记研究。
Br J Ind Med. 1985 Apr;42(4):281-4. doi: 10.1136/oem.42.4.281.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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The interaction of fatty acids with mammalian cytochrome c.脂肪酸与哺乳动物细胞色素c的相互作用。
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Chemical and photoelectron spectrometry analysis of the adsorption of phospholipid model membranes and red blood cell membranes on to chrysotile fibres.磷脂模型膜和红细胞膜在温石棉纤维上吸附的化学和光电子能谱分析
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