McPherson G A
Comput Programs Biomed. 1983 Aug-Oct;17(1-2):107-13. doi: 10.1016/0010-468x(83)90031-4.
EBDA is a computer program designed to process raw data (dpm) obtained from radioligand binding experiments into a form suitable for use by a non-linear curve fitting program. Processing of the data is facilitated by graphical representation in the form of Scatchard and Hill plots for saturation data, and competition curves and Hofstee plots for drug displacement studies. Preliminary estimates of binding constants required by a non-linear curve fitting program can also be obtained.
EBDA是一个计算机程序,旨在将从放射性配体结合实验中获得的原始数据(每分钟衰变数)处理成适合非线性曲线拟合程序使用的形式。通过以Scatchard图和Hill图的形式对饱和数据进行图形表示,以及以竞争曲线和Hofstee图的形式对药物置换研究数据进行图形表示,有助于数据的处理。还可以获得非线性曲线拟合程序所需的结合常数的初步估计值。