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牛轮状病毒血清型变异的证据。

Evidence for serotypic variation among bovine rotaviruses.

作者信息

Ojeh C K, Snodgrass D R, Herring A J

出版信息

Arch Virol. 1984;79(3-4):161-71. doi: 10.1007/BF01310809.

DOI:10.1007/BF01310809
PMID:6320775
Abstract

Eight field strains of calf rotavirus from the U.K. were compared by neutralisation tests, using convalescent and hyperimmune antisera. Seven of these strains cross-reacted and were considered to be of one serotype, while the 8th was distinguished by a greater than 20-fold two-way difference in neutralisation titre suggesting a second serotype. Three widely-distributed reference strains (U.K., Northern Ireland and Lincoln) cross-reacted with the strains in the dominant serotype, as did 33 of 42 other field calf rotavirus strains. Nine field strains failed to cross-react with either serotype, suggesting the existence of other potential serotypes in the calf population.

摘要

利用恢复期血清和高免疫血清,通过中和试验对来自英国的8株犊牛轮状病毒野毒株进行了比较。其中7株毒株发生交叉反应,被认为属于同一血清型,而第8株毒株在中和效价上具有大于20倍的双向差异,表明存在第二种血清型。3株广泛分布的参考毒株(英国、北爱尔兰和林肯)与优势血清型中的毒株发生交叉反应,42株其他犊牛轮状病毒野毒株中的33株也是如此。9株野毒株与这两种血清型均未发生交叉反应,提示犊牛群体中存在其他潜在血清型。

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Infect Immun. 1983 Jun;40(3):851-5. doi: 10.1128/iai.40.3.851-855.1983.
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Genetic heterogeneity within individual bovine rotavirus isolates.单个牛轮状病毒分离株内的基因异质性。
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