Gyte G M, Watkins S M
J Clin Pathol. 1978 Feb;31(2):125-8. doi: 10.1136/jcp.31.2.125.
Lymphocyte transformation to phytohaemagglutinin (PHA) was measured simultaneously by two methods (heparin and methyl cellulose) in 16 patients with non-lymphoid cancer and 21 normal subjects. Twelve cancer patients showed transformation levels below the normal heparin range, but only two patients showed levels below the normal methyl cellulose range. These findings suggest that in interpreting lymphocyte transformation studies close attention should be given to the methods employed.
采用两种方法(肝素法和甲基纤维素法)同时检测了16例非淋巴细胞癌患者和21名正常受试者对植物血凝素(PHA)的淋巴细胞转化情况。12例癌症患者的转化水平低于正常肝素法范围,但只有2例患者的水平低于正常甲基纤维素法范围。这些发现表明,在解释淋巴细胞转化研究结果时,应密切关注所采用的方法。