• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大肠杆菌黄嘌呤鸟嘌呤磷酸核糖转移酶基因的核苷酸序列。

Nucleotide sequence of the xanthine guanine phosphoribosyl transferase gene of E. coli.

作者信息

Richardson K K, Fostel J, Skopek T R

出版信息

Nucleic Acids Res. 1983 Dec 20;11(24):8809-16. doi: 10.1093/nar/11.24.8809.

DOI:10.1093/nar/11.24.8809
PMID:6324102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC326625/
Abstract

The nucleotide sequence of the gpt coding for the enzyme xanthine guanine phosphoribosyl transferase has been determined. The gene codes for a protein of molecular weight 16,950. The construction of deletions in the gpt gene which can be used for the genetic analysis of mutations in the gpt gene, is described.

摘要

已确定编码黄嘌呤鸟嘌呤磷酸核糖基转移酶的gpt的核苷酸序列。该基因编码一种分子量为16,950的蛋白质。本文描述了可用于gpt基因突变遗传分析的gpt基因缺失构建。

相似文献

1
Nucleotide sequence of the xanthine guanine phosphoribosyl transferase gene of E. coli.大肠杆菌黄嘌呤鸟嘌呤磷酸核糖转移酶基因的核苷酸序列。
Nucleic Acids Res. 1983 Dec 20;11(24):8809-16. doi: 10.1093/nar/11.24.8809.
2
Nucleotide sequence of the Escherichia coli xanthine-guanine phosphoribosyl transferase gene.大肠杆菌黄嘌呤-鸟嘌呤磷酸核糖基转移酶基因的核苷酸序列。
Nucleic Acids Res. 1983 Dec 20;11(24):8817-23. doi: 10.1093/nar/11.24.8817.
3
Structural and functional organization of the gpt gene region of Escherichia coli.
Gene. 1984 Dec;32(1-2):243-9. doi: 10.1016/0378-1119(84)90052-0.
4
Nucleotide sequence and analysis of deletion mutants of the Escherichia coli gpt gene in plasmid pSV2 gpt.
Gene. 1984 Nov;31(1-3):309-13. doi: 10.1016/0378-1119(84)90228-2.
5
A dominant selectable marker for the construction of recombinant poxviruses.用于构建重组痘病毒的显性选择标记。
Gene. 1988 May 15;65(1):123-8. doi: 10.1016/0378-1119(88)90424-6.
6
Transient assay, by [3H]guanine incorporation of Escherichia coli xanthine-guanine phosphoribosyl transferase (GPT) in transfected human fibroblasts.瞬时分析,通过在转染的人成纤维细胞中用[3H]鸟嘌呤掺入大肠杆菌黄嘌呤-鸟嘌呤磷酸核糖转移酶(GPT)进行。
Gene. 1985;40(1):93-8. doi: 10.1016/0378-1119(85)90027-7.
7
Selectable insertion and deletion mutagenesis of the human cytomegalovirus genome using the Escherichia coli guanosine phosphoribosyl transferase (gpt) gene.
J Gen Virol. 1995 Sep;76 ( Pt 9):2151-60. doi: 10.1099/0022-1317-76-9-2151.
8
Sequence analysis of spontaneous mutations in a shuttle vector gene integrated into mammalian chromosomal DNA.整合到哺乳动物染色体DNA中的穿梭载体基因自发突变的序列分析。
Proc Natl Acad Sci U S A. 1987 May;84(10):3354-8. doi: 10.1073/pnas.84.10.3354.
9
Both early and late control sequences of SV40 and polyoma promote transcription of Escherichia coli gpt gene in transfected cells.SV40和多瘤病毒的早期及晚期控制序列均可促进转染细胞中大肠杆菌gpt基因的转录。
EMBO J. 1982;1(8):895-900. doi: 10.1002/j.1460-2075.1982.tb01268.x.
10
Localization of the xanthine guanine phosphoribosyl transferase gene (gpt) of E. coli in AS52 metaphase cells by fluorescence in situ hybridization.
Environ Mol Mutagen. 1994;24(3):176-80. doi: 10.1002/em.2850240306.

引用本文的文献

1
Delivery method, target gene structure, and growth properties of target cells impact mutagenic responses to reactive nitrogen and oxygen species.递送方法、靶基因结构和靶细胞的生长特性会影响活性氮和氧物种引起的突变反应。
Chem Res Toxicol. 2012 Apr 16;25(4):873-83. doi: 10.1021/tx2004882. Epub 2012 Feb 21.
2
Functional analysis of the transcriptional control regions of the copia transposable element.果蝇copia转座因子转录控制区的功能分析
EMBO J. 1986 Sep;5(9):2349-2354. doi: 10.1002/j.1460-2075.1986.tb04503.x.
3
Hormonal and developmental specificities of transcription lie within a 1.5 kb region 5' to the ecdysone inducible Drosophila P1 gene.转录的激素和发育特异性位于蜕皮激素诱导的果蝇 P1 基因的 5'端的 1.5 kb 区域内。
EMBO J. 1986 Mar;5(3):583-8. doi: 10.1002/j.1460-2075.1986.tb04250.x.
4
Linkage map of Escherichia coli K-12, edition 10: the traditional map.大肠杆菌K-12连锁图谱,第10版:传统图谱。
Microbiol Mol Biol Rev. 1998 Sep;62(3):814-984. doi: 10.1128/MMBR.62.3.814-984.1998.
5
Cloning and expression of the hypoxanthine-guanine phosphoribosyltransferase gene from Trypanosoma brucei.布氏锥虫次黄嘌呤-鸟嘌呤磷酸核糖转移酶基因的克隆与表达
Nucleic Acids Res. 1993 Nov 25;21(23):5431-8. doi: 10.1093/nar/21.23.5431.
6
Cloning of a guanosine-inosine kinase gene of Escherichia coli and characterization of the purified gene product.大肠杆菌鸟苷-肌苷激酶基因的克隆及纯化基因产物的特性分析。
J Bacteriol. 1995 Sep;177(17):4921-6. doi: 10.1128/jb.177.17.4921-4926.1995.
7
Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens.致癌性镍通过染色质浓缩和DNA甲基化使基因表达沉默:一种表观遗传致癌物的新模型。
Mol Cell Biol. 1995 May;15(5):2547-57. doi: 10.1128/MCB.15.5.2547.
8
Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement.小鼠腺嘌呤磷酸核糖转移酶基因的核苷酸序列及结构:动物和细菌磷酸核糖转移酶共有编码区的存在,其内含子/外显子排列可变。
Proc Natl Acad Sci U S A. 1985 May;82(9):2731-5. doi: 10.1073/pnas.82.9.2731.
9
Sequence analysis of spontaneous mutations in a shuttle vector gene integrated into mammalian chromosomal DNA.整合到哺乳动物染色体DNA中的穿梭载体基因自发突变的序列分析。
Proc Natl Acad Sci U S A. 1987 May;84(10):3354-8. doi: 10.1073/pnas.84.10.3354.
10
DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.大肠杆菌在体内暴露于N-甲基-N-亚硝基脲或N-乙基-N-亚硝基脲后DNA碱基变化及烷基化情况。
Proc Natl Acad Sci U S A. 1987 Jan;84(2):344-8. doi: 10.1073/pnas.84.2.344.

本文引用的文献

1
Further correlations of the lacI genetic map with the DNA sequence.
J Mol Biol. 1981 Nov 25;153(1):65-6. doi: 10.1016/0022-2836(81)90526-x.
2
Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.筛选表达编码黄嘌呤 - 鸟嘌呤磷酸核糖转移酶的大肠杆菌基因的动物细胞。
Proc Natl Acad Sci U S A. 1981 Apr;78(4):2072-6. doi: 10.1073/pnas.78.4.2072.
3
Analysis at the sequence level of mutations induced by the ultimate carcinogen N-acetoxy-N-2-acetylaminofluorene.对终极致癌物N-乙酰氧基-N-2-乙酰氨基芴诱导的突变进行序列水平分析。
Environ Health Perspect. 1983 Mar;49:135-40. doi: 10.1289/ehp.8349135.
4
Purification and characterization of Escherichia coli guanine-xanthine phosphoribosyltransferase produced by a high efficiency expression plasmid utilizing a lambda PL promoter and CI857 temperature-sensitive repressor.利用λPL启动子和CI857温度敏感型阻遏物的高效表达质粒产生的大肠杆菌鸟嘌呤-黄嘌呤磷酸核糖基转移酶的纯化及特性分析
J Biol Chem. 1983 Jun 25;258(12):7469-75.
5
The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements.SV40 72碱基对重复序列优先增强从近端天然或替代启动子元件起始的转录。
Cell. 1983 Feb;32(2):503-14. doi: 10.1016/0092-8674(83)90470-1.
6
Expression of the herpes thymidine kinase gene in Xenopus laevis oocytes: an assay for the study of deletion mutants constructed in vitro.疱疹胸苷激酶基因在非洲爪蟾卵母细胞中的表达:一种用于研究体外构建的缺失突变体的检测方法。
Nucleic Acids Res. 1980 Dec 20;8(24):5931-48. doi: 10.1093/nar/8.24.5931.
7
Expression of a bacterial gene in mammalian cells.细菌基因在哺乳动物细胞中的表达。
Science. 1980 Sep 19;209(4463):1422-7. doi: 10.1126/science.6251549.
8
DNA base sequence changes induced by bromouracil mutagenesis of lambda phage.由λ噬菌体的溴尿嘧啶诱变诱导的DNA碱基序列变化。
J Mol Biol. 1982 Jul 25;159(1):19-33. doi: 10.1016/0022-2836(82)90029-8.
9
Factors governing the expression of a bacterial gene in mammalian cells.控制细菌基因在哺乳动物细胞中表达的因素。
Mol Cell Biol. 1981 May;1(5):449-59. doi: 10.1128/mcb.1.5.449-459.1981.
10
The use of thin acrylamide gels for DNA sequencing.用于DNA测序的薄丙烯酰胺凝胶的使用。
FEBS Lett. 1978 Mar 1;87(1):107-10. doi: 10.1016/0014-5793(78)80145-8.