临床分离的肠球菌对链霉素的核糖体耐药性。
Ribosomal resistance of clinical enterococcal to streptomycin isolates.
作者信息
Eliopoulos G M, Farber B F, Murray B E, Wennersten C, Moellering R C
出版信息
Antimicrob Agents Chemother. 1984 Mar;25(3):398-9. doi: 10.1128/AAC.25.3.398.
Abstract
The mechanism of high-level resistance to streptomycin was studied in 12 clinical isolates of Streptococcus faecalis. Six strains produced streptomycin-modifying enzymes. Each of three enzyme-negative strains tested demonstrated ribosomal resistance to streptomycin. Lack of ribosomal susceptibility is a significant cause of high-level streptomycin resistance among clinical enterococcal isolates.
摘要
对12株粪肠球菌临床分离株中高水平链霉素耐药机制进行了研究。6株产生链霉素修饰酶。所检测的3株酶阴性菌株中的每一株都表现出对链霉素的核糖体耐药性。核糖体敏感性缺乏是临床肠球菌分离株中高水平链霉素耐药的一个重要原因。
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